Human and Chimpanzee Nucleotide Diversity

Abstract

Nucleotide diversity is a measure of deoxyribonucleic acid (DNA) polymorphism in a population that is based on pairwise DNA sequence comparisons. The extent of nucleotide diversity is shaped by the mutation rate and selection but also by the demographic history of a population. Thus, studies of nucleotide diversity in humans and their closest evolutionary relative, the chimpanzee, shed light on the population history of these species.

Keywords: nucleotide diversity; selection; mutation rate; population subdivision, effective population size

Figure 1.

Histogram of nucleotide diversity estimates (as described in Table ) for mtDNA (a) and the two nuclear loci HOXB6 and Xq13.3 (b).

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How to Cite close
Kaessmann, Henrik(Mar 2008) Human and Chimpanzee Nucleotide Diversity. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005081.pub2]