László Patthy, Hungarian Academy of Sciences, Budapest, Hungary
Published online: May 2008
DOI: 10.1002/9780470015902.a0005087.pub2
Exon shuffling through recombination in spliceosomal introns had a major role in the evolution of multidomain proteins associated with multicellularity of metazoa.
Keywords: intronic recombination; chimeric gene; exon duplication; exon insertion; spliceosomal intron
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| Doolittle WF (1978) Genes in pieces: were they ever together? Nature 272: 581–582. | |
| Logsdon JM (1998) The recent origins of spliceosomal introns revisited. Current Opinion in Genetics & Development 8: 637–648. | |
| book Patthy L (1995) Protein Evolution by Exon Shuffling. New York: Springer. | |
| book Patthy L (1999, 2007) Protein Evolution. Oxford, UK: Blackwell Science. | |
| Sharp PA (1985) On the origin of RNA splicing and introns. Cell 42: 397–400. | |
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