Gross Insertions and Microinsertions in Evolution

Abstract

Gross insertions and microinsertions are a cause of human inherited disease but have also occurred during vertebrate evolution. For both microinsertions and the insertion of transposable elements, mechanistic models that have explanatory value in the context of genetic disease are also useful to account for the nature and location of evolutionary insertions.

Keywords: gross insertions; microinsertions; microinsertion polymorphisms; indels; transposable elements; evolution

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Further Reading

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Web Links

Chorionic gonadotropin, beta polypeptide (CGB); Locus ID: 1082. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=1082

Luteinizing hormone beta polypeptide (LHB); Locus ID: 3972. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=3972

Transaldolase 1 (TALDO1); Locus ID: 6888. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=6888

Chorionic gonadotropin, beta polypeptide (CGB); MIM number: 118860. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?118860

Luteinizing hormone beta polypeptide (LHB); MIM number: 152780. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?152780

Transaldolase 1 (TALDO1); MIM number: 602063. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?602063

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How to Cite close
Cooper, David N(Jul 2006) Gross Insertions and Microinsertions in Evolution. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005095]