Evolution: Neutralist View


The neutralist view of molecular evolution maintains that the vast amount of molecular variation seen in natural populations is largely due to neutral mutations.

Keywords: molecular; variation; evolution; selection; neutral theory

Further Reading

Ewens WJ (1977) Population genetics theory in relation to the neutralist‐selectionist controversy. Advances in Human Genetics 8: 67–134.

Kimura M (1983) The Neutral Theory of Molecular Evolution. Cambridge, UK: Cambridge University Press.

Kreitman M and Akashi H (1995) Molecular evidence for natural selection. Annual Review of Ecology and Systematics 26: 403–422.

Ohta T (1992) The nearly neutral theory of molecular evolution. Annual Review of Ecology and Systematics 23: 263–286.

Sayer SA, Dykhuizen DE and Hartl DL (1987) A confidence interval for the number of selectively neutral amino acid polymorphisms. Proceedings of the National Academy of Sciences of the USA 84: 6225–6228.

Sunyaev S, Kondrashov FA, Bork P and Ramensky V (2003) Impact of selection, mutation rate and genetic drift on human genetic variation. Human Molecular Genetics 12: 3325–3330.

Contact Editor close
Submit a note to the editor about this article by filling in the form below.

* Required Field

How to Cite close
Wagner, Andreas(Dec 2007) Evolution: Neutralist View. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005106.pub2]