Coevolution: Molecular

Molecular coevolution is an ongoing process by which a change in the sequence or function of a nucleic acid or protein molecule alters the selective effect of substitutions in another molecule or at other sites in the same molecule or of changes in the function of another molecule.

Keywords: host defence; ligand/receptor binding; selection; nonsynonymous substitution; statistical genetics

 References
    Adkins RM, Fain JN, Krushkal J et al. (2007a) Association between paternally inherited haplotypes upstream of the insulin gene and umbilical cord IGF-II levels. Pediatric Research 62: 451–455.
    Adkins RM, Honeycutt RL and Disotell TR (1996) Evolution of eutherian cytochrome c oxidase subunit II: heterogeneous rates of protein evolution and altered interaction with cytochrome c. Molecular Biology and Evolution 13: 1393–1404.
    other Adkins RM, Krushkal J, Klauser CK et al. (2007b) Association between small for gestational age and paternally inherited 5¢ insulin haplotypes. International Journal of Obesity (in press).
    Bayona-Bafaluy MP, Müller S and Moraes CT (2005) Fast adaptive evolution of nuclear and mitochondrial subunits of ATP synthetase in orangutan. Molecular Biology and Evolution 22: 716–724.
    Buck MJ and Atchley WR (2005) Networks of coevolving sites in structural and functional domains. Molecular Biology and Evolution 22: 1627–1634.
    Choi SS, Li W and Lahn BT (2005) Robust signals of coevolution of interacting residues in mammalian proteomes identified by phylogeny-aided structural analysis. Nature Genetics 37: 1367–1371.
    Evers R and Grummt I (1995) Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-I. Proceedings of the National Academy of Sciences of the USA 92: 5827–5831.
    Fares MA and Travers SAA (2006) A novel method for detecting intramolecular coevolution: adding a further dimension to selective constraints analyses. Genetics 173: 9–23.
    Galindo BE, Vacquier VD and Swanson WJ (2003) Positive selection in the egg receptor for abalone sperm lysine. Proceedings of the National Academy of Science of the USA 100: 4639–4643.
    Kalscheuer VM, Mariman EC, Schepens MT, Rehder H and Ropers H-H (1993) The insulin-like-growth factor type-2 receptor gene is imprinted in the mouse but not in humans. Nature Genetics 5: 74–78.
    Kenyon L and Moraes CT (1997) Expanding the functional human mitochondrial DNA database by the establishment of primate xenomitochondrial cybrids. Proceedings of the National Academy of Sciences of the USA 94: 9131–9135.
    Li Y, Wallis M and Zhang Y-P (2005) Episodic evolution of prolactin receptor gene in mammals: coevolution with its ligand. Journal of Molecular Endocrinology 35: 411–419.
    Liu J-C, Makova KD, Adkins RM, Gibson S and Li W-H (2001) Episodic evolution of growth hormone in primates and emergence of the species specificity of human growth hormone receptor. Molecular Biology and Evolution 18: 945–953.
    Moyle WR, Campbell RK, Myers RV et al. (1994) Co-evolution of ligand–receptor pairs. Nature 368: 251–255.
    Osheroff N, Speck SH, Margoliash E et al. (1983) The reaction of primate cytochromes c with cytochrome c oxidase. Analysis of the polarographic assay. Journal of Biological Chemistry 258: 5731–5738.
    Pollock DD, Taylor WR and Goldman N (1999) Coevolving protein residues: maximum likelihood identification and relationship to structure. Journal of Molecular Biology 287: 187–198.
    Schmidt TR, Wildman DE, Uddin M et al. (2005) Rapid electrostatic evolution at the binding site for cytochrome c on cytochrome c oxidase in anthropoid primates. Proceedings of the National Academy of Sciences of the USA 102: 6379–6384.
    Shields DC, Harmon DL and Whitehead AS (1996) Evolution of hemopoietic ligands and their receptors. Influence of positive selection on correlated replacements throughout ligand and receptor proteins. Journal of Immunology 156: 1062–1070.
    Swanson WJ and Vacquier VD (1998) Concerted evolution in an egg receptor for a rapidly evolving abalone sperm protein. Science 281: 710–712.
    Wilkins JF and Haig D (2001) Genomic imprinting of two antagonistic loci. Proceedings of the Royal Society of London, Series B 268: 1861–1867.
    Xu Y, Goodyer CG, Deal C and Polychronakos C (1993) Functional polymorphism in the parental imprinting of the human IGF2R gene. Biochemical and Biophysical Research Communications 197: 747–754.
    Yi S, Bernat B, Pal G, Kossiakoff A and Li W-H (2002) Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones. Molecular Biology and Evolution 19: 1083–1092.
 Further Reading
    Dutheil J, Pupko T, Jean-Marie A and Galtier N (2005) A model-based approach for detecting coevolving positions in a molecule. Molecular Biology and Evolution 22: 1919–1928.
    Gilbert SC, Plebanski M, Gupta S et al. (1998) Association of malaria parasite population structure, HLA, and immunological antagonism. Science 279: 1173–1177.
    Gobel U, Sander C, Schneider R and Valencia A (1994) Correlated mutations and residue contacts in proteins. Proteins: Structure Function and Genetics 18: 309–317.
    Hughes AL and Yeager M (1997) Coordinated amino acid changes in the evolution of mammalian defensins. Journal of Molecular Evolution 44: 675–682.
    Murphy PM (1993) Molecular mimicry and the generation of host defense protein diversity. Cell 72: 823–826.
    Nagel E (1994) How frequent are correlated changes in families of protein sequences? Proceedings of the National Academy of Sciences of the USA 91: 98–102.
    Sansonetti PJ and Di Santo JP (2007) Debugging how bacteria manipulate the immune response. Immunity Review 26: 149–161.
    Vacquier VD, Swanson WJ and Lee Y-H (1997) Positive Darwinian selection on two homologous fertilization proteins: what is the selective pressure driving their divergence? Journal of Molecular Evolution 44(suppl. 1): S15–S22.
Contact Editor close
Submit a note to the editor about this article by filling in the form below.

* Required Field

How to Cite close
Adkins, Ronald M(Mar 2008) Coevolution: Molecular. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005116.pub2]