References
Bjorkman PJ,
Saper MA,
Samraoui B et al.
(1987)
Structure of the human class I histocompatibility antigen, HLA‐A2.
Nature
329:
506–512.
Brown JH,
Jardetsky T,
Saper MA et al.
(1993)
Three‐dimensional structure of the human class II histocompatibility antigen HLA‐DR1.
Nature
364:
33–39.
Cadavid LF,
Shufflebotham C,
Ruiz FJ et al.
(1997)
Evolutionary instability of the major histocompatibility complex class I loci in New World primates.
Proceedings of the National Academy of Sciences of the United States of America
94:
14536–14541.
Carrington M,
Nelson GW,
Martin MP et al.
(1999)
HLA and HIV‐1: heterozygote advantage and B*35‐Cw*04 disadvantage.
Science
283:
1748–1752.
Cereb N,
Hughes AL and
Yang SY
(1997)
Locus‐specific conservation of the HLA class I introns by intralocus recombination.
Immunogenetics
47:
30–36.
Doherty PC and
Zinkernagel RM
(1975)
Enhanced immunologic surveillance in mice heterozygous at the H‐2 gene complex.
Nature
256:
50–52.
Hedrick PW and
Thompson G
(1983)
Evidence for balancing selection at HLA.
Genetics
104:
449–456.
Hughes AL and
Nei M
(1988)
Pattern of nucleotide substitution at MHC class I loci reveals overdominant selection.
Nature
335:
167–170.
Hughes AL and
Nei M
(1989)
Evolution of the major histocompatibility complex: independent origin of nonclassical class I genes in different groups of mammals.
Molecular Biology and Evolution
6:
559–579.
Mayer WE,
Jonker D,
Klein D et al.
(1988)
Nucleotide sequence of chimpanzee MHC class I alleles: evidence for transspecies mode of evolution.
EMBO Journal
7:
2765–2774.
Further Reading
Bontrop RE
(2006)
Comparative genetics of MHC polymorphisms in different primate species: duplications and deletions.
Human Immunology
67:
388–397.
Flajnik MF,
Ohta Y,
Namikawa‐Yamada C and
Nonaka M
(1999)
Insight into the primordial MHC from studies in ectothermic vertebrates.
Immunological Reviews
167:
59–67.
Hughes AL
(1999)
Adaptive Evolution of Genes and Genomes.
New York, NY: Oxford University Press.
Hughes AL,
Hughes MK,
Howell CY and
Nei M
(1994)
Natural selection at the class II major histocompatibility complex loci of mammals.
Philosophical Transactions of the Royal Society of London B
345:
359–367.
Hughes AL and
Nei M
(1990)
Evolutionary relationships of class II MHC genes in mammals.
Molecular Biology and Evolution
7:
491–514.
Hughes AL and
Yeager M
(1998)
Natural selection at the major histocompatibility complex loci of vertebrates.
Annual Review of Genetics
32:
415–435.
Hughes AL,
Yeager M,
Ten Elshof A and
Chorney MJ
(1999)
A new taxonomy of mammalian MHC class I molecules.
Immunology Today
20:
22–26.
Kelley J,
Walter L and
Trowsdale J
(2005)
Comparative genomics of major histocompatibility complexes.
Immunogenetics
56:
683–695.
Klein J
(1986)
Natural History of the Major Histocompatibility Complex.
New York, NY: Wiley.
McDevitt HO
(2000)
Discovering the role of the major histocompatibility complex in the immune response.
Annual Review of Immunology
18:
1–17.
Meyer D,
Single RM,
Mack SJ,
Erlich HA and
Thomson G
(2006)
Signatures of demographic history and natural selection in the human major histocompatibility complex loci.
Genetics
173:
2121–2142.
Nei M,
Gu X and
Sitnikova T
(1997)
Evolution by the birth‐and‐death process in multigene families of the vertebrate immune system.
Proceedings of the National Academy of Sciences of the United States of America
94:
7799–7806.
Parham P and
Ohta T
(1996)
Population biology of antigen presentation by MHC class I molecules.
Science
272:
67–74.
Shiina T,
Ota M,
Shimizu S et al.
(2006)
Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
Genetics
173:
1555–1570.