Molecular Machines and Human Disorders

Abstract

Living cells contain various kinds of molecular machine constructed from protein molecules, sometimes with nucleic acid molecules. They work for free energy conversion, information transfer and the performance of specific physical and chemical processes.

Keywords: ATP synthetase; sliding machine; cargo transport; proteasome; chaperonin; syndromes; neuropathy; cardiomyopathy; deafness; myosin family; troponins

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Oosawa, Fumio(Sep 2005) Molecular Machines and Human Disorders. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005168]