Human Genome Diversity Project (HGDP)

Abstract

The Human Genome Diversity Project was proposed as a public project to collect and analyze DNA samples from diverse human populations. While never realized as an actual DNA collection, the investigation of human genetic variation largely has been taken over by more biomedically oriented initiatives.

Keywords: genetic variation; diversity; indigenous people; bioethics; race; ethnicity

References

Cann HM, de Toma C, Cazes L et al. (2002) A human genome diversity cell line panel. Science 296: 261–262.

Cavalli‐Sforza LL, Wilson AC, Cantor CR, Cook‐Deegan RM and King MC (1991) Call for a worldwide survery of human genetic diversity – a vanishing opportunity for the Human Genome Project. Genomics 11(2): 490–491.

Cunningham H (1998) Colonial encounters in postcolonial contexts: patenting indigenous DNA and the Human Genome Diversity Project. Critical Anthropology 18(2): 205–233.

Dodson M and Williamson R (1999) Indigenous peoples and the morality of the Human Genome Diversity Project. Journal of Medical Ethics 25(2): 204–208.

Dukepoo FC (1998) The trouble with the Human Genome Diversity Project. Molecular Medicine Today 4(6): 242–243.

Foster MW and Sharp RR (2002) Race, ethnicity, and genomics: social classifications as proxies of biological heterogeneity. Genetic Research 12(6): 844–850.

Greely HT (2001) Human genome diversity: what about the other human genome project? Nature Review of Genetics 2(3): 222–227.

Kidd JR, Kidd KK and Weiss KM (1993) Human genome diversity initiative. Human Biology 65(1): 1–6.

Lock M (1994) Interrogating the Human Genome Diversity Project. Social Science and Medicine 39(5): 603–606.

Lone Dog L (1999) Whose genes are they? The Human Genome Diversity Project. Journal of Health and Social Policy 10(4): 51–66.

National Research Council (1998) Evaluating Human Genetic Diversity. Washington DC: National Academy of Science.

Reardon J (2001) The Human Genome Diversity Project: a case study in coproduction. Social Studies of Science 31(3): 357–388.

Risch N, Burchard E, Ziv E and Tang H (2002) Categorization of humans in biomedical research: genes, race and disease. Genome Biology July 1; 3(7): comment2007.1–2007. 12.

Weiss KM and Clark AG (2002) Linkage disequilibrium and the mapping of complex human traits. Trends in Genetics 18(1): 19–24.

Wilson JF, Weale ME, Smith AC et al. (2001) Population genetic structure of variable drug response. Nature Genetics 29(3): 265–269.

Further Reading

Cavalli‐Sforza LL (2005) The Human Genome Diversity Project: past, present and future. Nature Reviews. Genetics 6: 333–340.

M'Charek A (2005) The Human Genome Diversity Project. An Ethnography of Scientific Practice. Cambridge University Press. pp. 1–224.

The Human Genome Diversity Project website is to be found at http://shgc.stanford.edu/hgdp

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How to Cite close
Foster, Morris W(Jul 2008) Human Genome Diversity Project (HGDP). In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005173.pub2]