Gene Expression Databases

Alvis Brazma, European Molecular Biology Laboratory, Cambridge, UK
Ugis Sarkans, European Molecular Biology Laboratory, Cambridge, UK

Published online: December 2007

DOI: 10.1002/9780470015902.a0005248.pub2

Gene expression databases store information about the absolute or relative abundance of gene transcription products in various biological samples, such as cells from a particular tissue in a particular organism, or a particular cell line. These databases allow one to access, select, retrieve and combine for analysis gene expression datasets generated by one's own or other laboratories.

Keywords: gene expression; microarrays; database

Figure 1. Conceptual design of microarray-based gene expression database ArrayExpress.
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 References
    Brazma A, Hingamp P, Quackenbush J et al. (2001) Minimum information about a microarray experiment (MIAME)–toward standards for microarray data. Nature Genetics 29: 365–371.
    Brazma A, Robinson A, Cameron G and Ashburner M (2000) One-stop shop for microarray data. Nature 403: 699–700.
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    Rayner TF, Rocca-Serra P, Spellman PT et al. (2006) A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB. BMC Bioinformatics 7: 489.
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    Spellman PT, Miller M, Stewart J et al. (2002) Design and implementation of microarray gene expression markup language (MAGE-ML). Genome Biology 3(9): research 0046.1–0046.9.
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 Further Reading
    other The chipping forecast II (2002) Nature Genetics (suppl. 4) , vol 32.

Related Sub-Topics:

Bioinformatics | Techniques and Tools in Clinical Genetics | Gene Expression Profiling of Genetic Disease | Bioinformatics and Genetic Disease | Techniques and Tools in Molecular Biology | Computational Molecular Biology
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Article Title: Gene Expression Databases
 
How to Cite close
Brazma, Alvis, and Sarkans, Ugis(Dec 2007) Gene Expression Databases. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005248.pub2]