Alcoholism: Collaborative Study on the Genetics of Alcoholism (COGA)

Abstract

Twin, adoption and family studies provide evidence for a genetic component for the susceptibility to alcoholism. The Collaborative Study on the Genetics of Alcoholism (COGA) is a comprehensive family study aimed at identifying specific genetic risk factors.

Keywords: alcohol dependence; linkage analyses; event‐related potential; candidate gene

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Web Links

Dopamine receptor D2 (DRD2); Locus ID: 1813. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=1813

Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4); Locus ID: 6532. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=6532

Alcohol dehydrogenase 1C (class I), gamma polypeptide (ADH1C); Locus ID 126. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=126

Dopamine receptor D2 (DRD2); MIM number: 126450. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?126450

Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4); MIM number: 182138. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?182138

Alcohol dehydrogenase 1C (class I), gamma polypeptide (ADH1C); MIM number: 103730. OMIM: http://www3.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?103730

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How to Cite close
Rice, John P, Saccone, Nancy L, Foroud, Tatiana, Edenberg, Howard J, Nurnberger, John I, Goate, Alison, Crowe, Raymond R, Hesselbrock, Victor, Schuckit, Marc, Porjesz, Bernice, Reich, Theodore, and Begleiter, Henri(Jul 2006) Alcoholism: Collaborative Study on the Genetics of Alcoholism (COGA). In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005294]