Comparative Human Genomics

Abstract

Comparative genomics involves the comparison of features of completely sequenced (or nearly so) genomes. Comparative sequence analyses facilitate both the functional annotation of genomes and whole‐genome approaches to evolutionary issues. We present a review of the field of comparative genomics and point out how the comparative approach can be used to help better understand the human genome sequence.

Keywords: molecular evolution; natural selection; transposable elements; horizontal gene transfer; noncoding DNA; individual genomics

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Jordan, I King, and Koonin, Eugene V(Jul 2008) Comparative Human Genomics. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005296.pub2]