Male‐driven Evolution


If the number of germ‐line cell divisions has an effect on the mutation rate, for example owing to replication errors, we might expect the mutation rate of the two sexes to differ. Recent estimates from human and other primates suggest that this difference corresponds to a male bias of a factor of approximately 5.

Keywords: germ line; mutation rate; sex chromosomes; male bias; polymorphism


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Further Reading

Li WH, Yi S and Makova K (2002) Male‐driven evolution. Current Opinion in Genetics & Development 12: 650–656.

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Ellegren, Hans(Apr 2008) Male‐driven Evolution. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0005303.pub2]