Restriction Fragment Length Polymorphism (RFLP)


A restriction fragment length polymorphism is a fragment produced by restriction enzyme digestion of genomic deoxyribonucleic acid, whose length is variable because of a sequence polymorphism that affects the presence or location of a target site for the stated restriction enzyme.

Keywords: genome map; genetic linkage map; polymorphism; marker; restriction enzyme; physical mapping

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Dear, Paul H(Sep 2005) Restriction Fragment Length Polymorphism (RFLP). In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0005358]