Josephine Hoh, Rockefeller University, New York, USA
Jurg Ott, Rockefeller University, New York, USA
Published online: September 2005
DOI: 10.1038/npg.els.0005360
Random occurrences of crossovers along a chromosome permit definition of a genetic distance. Such distances are used to create genetic maps and to localize disease genes on these maps.
Keywords: recombination; crossover; chiasma; genetic marker; disease gene
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Figure 1.
Effects of a crossover between two loci on resulting gametes (right‐hand side) and corresponding genetic phenotypes (left side), where R=recombinant and N=nonrecombinant gamete. |
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Further Reading
Strachan T and Read AP (1996) Human Molecular Genetics. New York, NY: Wiley‐Liss.
Sturtevant AH (2001) A History of Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
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