Multilocus Linkage Analysis


With multilocus linkage analysis, more than two loci are simultaneously considered for linkage. When mapping a disease gene relative to a group of markers with known intermarker recombination fractions, it is possible to perform parametric (lod score) as well as nonparametric analysis.

Keywords: multipoint; interference; parametric analysis; lod score; nonparametric analysis


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Terwilliger JD and Ott J (1984) Handbook of Human Genetic Linkage. Baltimore, MD: Johns Hopkins University Press.

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Strauch, Konstantin(Jan 2006) Multilocus Linkage Analysis. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0005404]