Statistical Methods in Physical Mapping

Sophie Schbath, Institut National de la Recherche Agronomique, Jouy-en-Josas, France

Published online: July 2006

DOI: 10.1038/npg.els.0005434

Statistical methods are used to predict the progress of a physical mapping project in terms of the number and size of the contigs and the proportion of genome covered by contigs.

Keywords: physical mapping; islands; genome coverage; Poisson process; coverage process

 References
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    Lander ES and Waterman MS (1988) Genomic mapping by fingerprinting random clones: a mathematical analysis. Genomics 2: 231–239.
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    Schbath S (1997) Coverage processes in physical mapping by anchoring random clones. Journal of Computational Biology 4: 61–82.
    Schbath S, Bossard N and Tavaré S (2000) The effect of nonhomogeneous clone length distribution on the progress of an STS mapping project. Journal of Computational Biology 7: 47–57.

Related Sub-Topics:

Techniques and Tools in Clinical Genetics | Statistical Methodology in Genetics | Techniques and Tools in Molecular Biology
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Article Title: Statistical Methods in Physical Mapping
 
How to Cite close
Schbath, Sophie(Jul 2006) Statistical Methods in Physical Mapping. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005434]