Population Genetics: Historical Aspects

Abstract

Understanding the extent of genetic variation among individuals within as well as across populations is the main objective of population genetic studies. The principles of population genetics have had a major role in studying evolutionary changes of genetic variation and in developing methods for gene discovery using genetic markers to evaluate disease risk in individuals.

Keywords: genetic variation; molecular evolution; polymorphism; gene mapping; human identification

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Further Reading

Cavalli‐Sforza LL, Menozzi P and Piazza A (1994) The History and Geography of Human Genes. Princeton, NJ: Princeton University Press.

Li WH (1997) Molecular Evolution. Sunderland, MA: Sinauer.

Nei M (1987) Molecular Evolutionary Genetics. New York, NY: Columbia University Press.

Provine WB (1971) Origins of Theoretical Population Genetics. Chicago, IL: University of Chicago Press.

Vogel F and Motulsky AG (1997) Human Genetics, 2nd edn New York, NY: Springer.

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How to Cite close
Chakraborty, Ranajit(Jul 2006) Population Genetics: Historical Aspects. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005439]