Medical Genetics: History

Abstract

Some notion of the rules of heredity in humans has existed for more than 2000 years; however, genetics as a true science was founded only in the second half of the nineteenth century, and has undergone recent rapid development. This knowledge is being increasingly used in medicine.

Keywords: biometric genetics; cytogenetics; clinical; genetic analysis; mendel's laws; twin studies

References

Barthelmess A (1952) Vererbungswissenschaft. Freiburg: Alber.

Bernstein F (1931) Zur Grundlegung der Chromosomentheorie der Vererbung beim Menschen. Zeitschrift für Induktive Abstammungs‐ und Vererbungslehre 57: 113–138.

Cremer T (1986) Von der Zellenlehre zur Chromosomentheorie. Berlin: Springer.

Galton F (1865) Hereditary talent and character. Macmillans Magazine 12: 157.

Garrod AE (1902) The incidence of alkaptonuria: a study in chemical individuality. The Lancet 2: 1616–1620.

Haldane JBS (1935) The rate of spontaneous mutation of a human gene. Journal of Genetics 31: 317–326.

Kuhn TS (1962) The Structure of Scientific Revolutions. Chicago, IL: University of Chicago Press.

Mendel GJ (1865) Versuche über Pflanzenhybriden. Brünn: Verhandlungen des Naturforschenden.

Mohr J (1954) A Study of Linkage in Man. Copenhagen: Munksgaard.

Motulsky AG (1959) Joseph Adams (1756–1818). Archives of Internal Medicine 104: 490–496.

Vogel F and Motulsky AG (1997) Human Genetics. Problems and Approaches, 3rd edn. Berlin: Springer.

Further Reading

Becker PE (ed.) (1964–1976) Humangenetik. Ein kurzes Handbuch, 5 vols Stuttgart: Georg Thieme.

Dunn LC (1962) Cross currents in the history of human genetics. American Journal of Human Genetics 14: 1–13.

Just G (ed.) (1939–1940) Handbuch der Erbbiologie des Menschen, 5 vols Berlin: Julius Springer.

Kühl S (1994) The Nazi Connection. Eugenics, American Racism, and German National Socialism Oxford, UK: Oxford University Press.

Lenz W (1968) Daten zur Geschichte der Humangenetik und ihrer Grundlagen. Becker PE (ed.) Humangenetik. Ein kurzes Handbuch, vol. 1, pp. 77–113. Stuttgart: Georg Thieme.

Neel JV (1994) Physician to the Gene Pool New York, NY: John Wiley.

Pearson K, Fisher RA, Penrose LS and Bell J (main editors) (1909–1958) Treasury of Human Inheritance London, UK: Durlau and Co. (later Cambridge, UK: Cambridge University Press).

Weindling PF (1989) Health, Race and German Politics between National Unification and Nazism 1870–1945 Cambridge, UK: Cambridge University Press.

Weingart P, Kroll J and Bayertz K (1988) Rasse, Blut und Gene Frankfurt: Suhrkamp.

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Vogel, Friedrich(Jan 2006) Medical Genetics: History. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005488]