Dolly and Polly

Abstract

Dolly, born in 1996, achieved notoriety by being the first mammal to be cloned from the nucleus of a fully differentiated cell, taken from the udder of an adult sheep. Polly, born a year after Dolly, was not only cloned but was also genetically transformed; that is, she carried an introduced gene that codes the protein factor IX, which is involved in blood clotting, which has huge therapeutic value.

Keywords: Dolly; Polly; cloning; pharming; nuclear transfer; reproductive cloning; therapeutic cloning

References

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Further Reading

House of Commons Science and Technology Committee (1997) The Cloning of Animals from Adult Cells, HC 373‐1. London, UK: HMSO.

Petersen A (2002) Replicating our bodies, losing our selves: news media portrayals of human cloning in the wake of Dolly. Body and Society 8(4): 71–90.

Ratala ML and Milgram AJ (1999) Cloning: For and Against. Chicago, IL: Open Court.

Wong DWS (1997) The ABCs of Gene Cloning New York, NY: Chapman & Hall.

Web Links

The Human Genetics Commission (HGC). Cloning Issues in Reproduction, Science and Medicine (issued January 1998) http://www.hgc.gov.uk/business_publications.htm#reports

PPL Therapeutics http://www.ppl‐therapeutics.com

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How to Cite close
Petersen, Alan(Sep 2006) Dolly and Polly. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005598]