Lindsay Prior, Cardiff University, Cardiff, UK
Published online: September 2006
DOI: 10.1002/9780470015902.a0005618
Risk assessment of adverse genetic outcomes involves complex decision-making procedures. Human values and expert judgments of various kinds, as well as scientific and/or mathematical knowledge and technological hardware, are all implicated in the assessment process.
Keywords: cancer; population genetics; referral criteria; risk; uncertainty
| References | |
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| Further Reading | |
| book Chapman CJ (1997) Cyrillic for Pedigree Drawing. Oxford, UK: Cherwell Scientific Publishing. | |
| Edwards A, Hood K, Mathews E, et al. (2000) The effectiveness of one-to-one risk-communication interventions in health care. A systematic review. Medical Decision Making 20: 290–297. | |
| book House of Commons Select Committee on Science and Technology. (2001) Fifth Report. London, UK: Her Majesty's Stationery Office. | |
| Pharoah PD, Stratton JF and Mackay J (1998) Screening for breast and ovarian cancer: the relevance of family history. British Medical Bulletin 54: 823–838. | |
| book Unwin N, Carr S, Leeson J and Pless-Mulloli T (1997) An Introductory Study Guide to Public Health and Epidemiology Buckingham, UK: Open University Press. | |
| Web Links | |
| ePath Genetic Health http://www.genetichealth.com | |
| ePath Apolipoprotein E (APOE). LocusID: 348. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=348 | |
| ePath Breast cancer 1, early onset (BRCA1). LocusID: 672. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=672 | |
| ePath Breast cancer 2, early onset (BRCA2). LocusID: 675. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=675 | |
| ePath Apolipoprotein E (APOE). MIM number: 107741. OMIM: http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?107741 | |
| ePath Breast cancer 1, early onset (BRCA1). MIM number: 113705. OMIM: http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?113705 | |
| ePath Breast cancer 2, early onset (BRCA2). MIM number: 600185. OMIM: http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?600185 | |
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