Annie Procter, Institute of Medical Genetics, Cardiff, UK
Published online: September 2006
DOI: 10.1002/9780470015902.a0005620
It is generally well recognized and accepted that opportunities exist to test individuals for genetic disorders; however, the application of such genetic testing during childhood is subject to controversy and debate.
Keywords: genetic testing; childhood testing; predictive test; presymptomatic test; carrier test; adult-onset disorders; consent
| References | |
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| Further Reading | |
| American Society of Human Genetics/American College of Medical Genetics (1995) ASHG/ACMG Report. Points to consider: ethical, legal and psychosocial implications of genetic testing in children and adolescents. American Journal of Human Genetics 57: 1233–1241. | |
| Balfour-Lynn I, Madge S and Dinwiddie R (1995) Testing carrier status in siblings of patients with cystic fibrosis. Archives of Disease in Childhood 72: 167–168. | |
| book Clarke A (ed.) (1998) The Genetic Testing of Children. Oxford, UK: BIOS Scientific Publishers. | |
| Davis DS (1998) Discovery of children's carrier status for recessive genetic disease: some ethical issues. Genetic Testing 2: 323–327. | |
| other Gillick versus West Norfolk and Wisbech Health Authority (1985) 3 All ER 402. | |
| Mitchell J, Capua A, Clow C and Scriver CR (1996) Twenty-year outcome analysis of genetic screening programs for Tay–Sachs and -thalassaemia disease carriers in high schools. American Journal of Human Genetics 59: 793–798. | |
| Mitchell J, Scriver CR, Clow C and Kaplan F (1993) What young people think and do when the option for cystic fibrosis carrier screening is available. Journal of Medical Genetics 30: 538–542. | |
| Welkenhuysen M, Evers-Kiebooms G, Decruyenaere M, et al. (1996) Adolescents' attitude towards carrier testing for cystic fibrosis and its relative stability over time. European Journal of Human Genetics 4: 52–62. | |
| Wertz DC, Fanos JH and Reilly PR (1994) Genetic testing for children and adolescents. Who decides? Journal of the American Medical Association 272: 875–881. | |
| Wertz DC and Reilly PR (1997) Laboratory policies and practices for the genetic testing of children: a survey of the Helix network. American Journal of Human Genetics 61: 1163–1168. | |
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