Gene Therapy: Ethics and Regulation

Abstract

Ethical and regulatory considerations are paramount in gene therapy, which is the deliberate introduction of genetic material into human somatic cells for therapeutic, prophylactic or diagnostic purposes.

References

Chadwick R (1998) Gene therapy. In: Kuhse H and Singer P (eds.) A Companion to Bioethics, chap. 19, pp. 189–197. Oxford, UK: Blackwells.

Clothier Committee (1992) Report of the Committee on the Ethics of Gene Therapy (Clothier Report, Cm 1788). London, UK: Her Majesty's Stationery Office.

Council of Europe (1997) Convention on Human Rights and Biomedicine. Oviedo: Council of Europe.

European Parliament (2001) Directive 2001/20/EC. Luxembourg: European Parliament and Council of European Union.

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GTAC (1998) Report on the Potential Use of Gene Therapy in Utero. London, UK: Gene Therapy Advisory Committee.

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Harris J (1992) Wonderwoman & Superman: The Ethics of Human Biotechnology. Oxford, UK: Oxford University Press.

Humpherys D, Eagan K, Akutsu H, et al. (2001) Epigenetic instability in ES cells and cloned mice. Science 293: 95–97.

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UNESCO (1997) Universal Declaration on the Human Genome and Human Rights. Paris: United Nations Educational, Scientific and Cultural Organization.

WMA (2000) Declaration of Helsinki, 5th revision. Edinburgh, UK: World Medical Association General Assembly.

Web Links

Gene Therapy Advisory Committee (GTAC) http://www.doh.gov.uk/genetics/gtac

Health and Safety Executive http://www.hse.gov.uk/

Medicines Control Agency http://www.mca.gov.uk/

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How to Cite close
Harrison, Michael T(Sep 2006) Gene Therapy: Ethics and Regulation. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005652]