Mass Spectrometry in Protein Characterization

Hanno Steen, Harvard Medical School, Boston, Massachusetts, USA
Akhilesh Pandey, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Published online: January 2006

DOI: 10.1038/npg.els.0005726

The complete complement of proteins in a cell, the proteome, is highly complex because a single protein can exist in several different forms. Mass spectrometry has emerged as the tool of choice for protein identification as well as for characterization of posttranslational modifications.

Keywords: mass spectrometry; ionization; posttranslational; modifications; phosphorylation; quantification; MALDI

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Related Sub-Topics:

Protein Structure | Mass Spectrometry | Posttranslational Modification
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Article Title: Mass Spectrometry in Protein Characterization
 
How to Cite close
Steen, Hanno, and Pandey, Akhilesh(Jan 2006) Mass Spectrometry in Protein Characterization. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005726]