Chromosome 3

Abstract

Human chromosome 3 is the third largest chromosome, containing ∼7% of the genetic material in the genome. This metacentric chromosome contains the most common fragile site as well as clusters of olfactory receptor and chemokine receptor genes.

Keywords: chromosome 3, gene mapping; comparative mapping; fragile site; genetic disease

References

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Further Reading

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Web Links

Baylor HGSC. Sequencing of chromosome 3 http://www.hgsc.bcm.tmc.edu

Center for Medical Genetics. Marshfield map http://research.marshfieldclinic.org/genetics

CGAP (Cancer Genome Anatomy Project). The National Cancer Institute has undertaken a Cancer Genome Anatomy Project. It is a repository molecular data for genes, chromosomes, and tissues in human and mouse http://cgap.nci.nih.gov

eGenome. eGenome is another representation of data for the human genome. The site emphasizes a map view of polymorphisms and transcribed sequences. http://egenome.chop.edu

Ensembl Genome Browser. This a highly detailed site created by the European Bioinformatics Group. Information from gene loci to SNPs to ESTs is represented in an interactive manner from the whole entity to the single nucleotide http://www.ensembl.org

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Fondation Jean Dausset – CEPH. CEPH–Genethon map http://www.cephb.fr

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Genome Sequencing Center. Fingerprint contig generated by Washington University http://genome.wustl.edu

Human Telomere Mapping and Sequencing Project. This site indicates the information available for human telomeres – clones that have been isolated and sequence that is available http://www.wistar.upenn.edu/Riethman

Max Planck Institute for Molecular Genetics. Sequencing projects http://seq.mpimg‐berlin‐dahlem.mpg.de/

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NCBI (National Center for Biotechnology Information) SNP; BACs that have been FISH‐mapped to chromosome 3; radiation hybrid map http://www.ncbi.nlm.nih.gov

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San Antonio Genome Center. Tiling path for chromosome 3 http://apollo.uthscsa.edu

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University of Washington Genome Center. This database has been key in constructing human BAC contigs. In addition the site provides information on regions it has sequenced as well as SNP and EST data http://www.genome.washington.edu

TCTA(T‐cell leukemia translocation altered gene); Locus ID: 6988. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=6988

TP63(tumor protein p63); Locus ID: 8626. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=8626

TCTA(T‐cell leukemia translocation altered gene); MIM number: 600690. OMIM: http://www3.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?600690

TP63(tumor protein p63); MIM number: 603273. OMIM: http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?cmd=entry&id=603273

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How to Cite close
Naylor, Susan L, and Garcia, Dawn K(Jan 2006) Chromosome 3. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005812]