Chromosome 7

Abstract

Human chromosome 7 is a submetacentric chromosome containing 5.3% of the genome. It is characterized by T‐cell receptor and homeobox A gene clusters and contains several imprinted genes.

Keywords: chromosome 7; disease; genes; maps; DNA sequence

References

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Further Reading

Ewart AK, Morris CA, Atkinson D, et al. (1993) Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome. Nature Genetics 1: 11–16.

Grzeschik KH, Tsui L‐C and Green ED (1993) Report and abstracts of the First International Workshop on Human Chromosome 7 Mapping 1993. Cytogenetics and Cell Genetics 65: 52–73.

International Molecular Genetic Study of Autism Consortium (1998) A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Human Molecular Genetics 7: 571–578.

Johnson E and Cotter FE (1997) Monosomy 7 and 7q‐associated with myeloid malignancy. Blood Reviews 1: 46–55.

Lander ES, Linton LM, Birren B, et al. (2001) Initial sequencing and analysis of the human genome. Nature 409: 860–921.

Osborne LR, Li M, Pober B, et al. (2001) A 1.5 million base pair inversion polymorphism in families with Williams–Beuren syndrome. Nature Genetics 3: 321–325.

Ridley M (1999) ‘Instinct’. chap. 7. Genome: The Autobiography of a Species in 23 Chapters, New York, NY: HarperCollins.

Scherer SW, Cheung J, MacDonald JR, et al. (2003) Human chromosome 7: DNA sequence and biology. Science [published online 10 April 2003].

Tsui L‐C (1988) Genetic markers on chromosome 7. Journal of Medical Genetics 25: 294–306.

Tsui L‐C and collaborators (1989) Cystic fibrosis: cloning and genetics. Science 245: 923–924, 1029, 1059–1065, 1066–1073, 1073–1080.

Tsui L‐C, Donis‐Keller H and Grzeschik K‐H (1994) Report of the Second International Workshop on Human Chromosome 7 mapping 1994. Cytogenetics and Cell Genetics 71: 2–31.

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Web Links

Genew Human Gene Nomenclature Database Search Engine. A gene‐based entry point into genomic/genetic as well as disease/phenotype information http://www.gene.ucl.ac.uk/cgi‐bin/nomenclature/searchgenes.pl

Human Genome Organization (HUGO). HUGO has established a reference website for chromosome 7 providing links to all other relevant sites housing information for that chromosome and the diseases that map to it http://www.gdb.org/hugo/chr7/

Online Mendelian Inheritance in Man (OMIM). http://www.ncbi.nlm.nih.gov/Omim/

The chromosome 7 Annotation Project. A new website to support research community initiatives for functional and medical annotation of human chromosome 7 has been established at http: //www.chr7.org/ This site contains a description of the complete sequence of human chromosome 7, a curated gene set as well as other features such as structural, functional and medical annotation data.

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How to Cite close
Scherer, Stephen W(Jan 2006) Chromosome 7. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005816]