Theologia Sarafidou, University of Thessaly, Larissa, Greece
Nicholas K Moschonas, University of Patra, Patra, Greece
Published online: July 2007
DOI: 10.1002/9780470015902.a0005819.pub2
Human chromosome 10 (HC10) corresponds to about 4.2% of the total genome length. Eighty-five of the 754 protein coding genes mapped to HC10 are associated with more than 100 genetic diseases. Susceptibility loci for 17 common multifactorial diseases, such as Alzheimer disease, type 1 diabetes and schizophrenia map to HC10.
Keywords: PTEN; RET; acute leukaemia; type 1 diabetes; overlapping genes
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Figure 1. Distribution of the molecular function of 754 protein coding genes of HC10 (Sarafidou and Moschonas, 2006, unpublished data).
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| References | |
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| Further Reading | |
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