Chromosome 11

Human chromosome 11 is a submetacentric chromosome that contains some 4% of the genome and a number of imprinted genes.

Keywords: chromosome 11; sequencing; imprinting; translocations; diseases

 References
    Broman KW, Murray JC, Sheffield VC, White RL and Weber JL (1998) Comprehensive human genetic maps: individual and sex-specific variation in recombination. American Journal of Human Genetics 63: 861–869.
 Further Reading
    Gaudray P, et al. (1999) Report on the Sixth International Workshop on Human Chromosome 11 Mapping 1998. Cyto-genetics and Cell Genetics 86: 167–186.
    International Genome Sequencing Consortium (2001) Initial sequencing and analysis of the human genome. Nature 409: 860–921.
    James MR, Richard 3rd CW, Schott JJ, et al. (1994) A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nature Genetics 8: 70–76.
    Maher ER and Reik W (2000) Beckwith–Wiedemann syndrome: imprinting in clusters revisited. Journal of Clinical Investigation 105: 247–252.
    Yu A, Zhao C, Fan Y, et al. (2001) Comparison of human genetic and sequence-based physical maps. Nature 409: 951–953.
    Zhang J, Qin S, Sait SNJ, et al. (2001) The pericentromeric region of human chromosome 11: evidence for a chromosome-specific duplication. Cytogenetics and Cell Genetics 94: 137–141.
 Web Links
    ePath Atlas of Genetics and Cytogenetics in Oncology and Haematology. http://www.infobiogen.fr/services/chromcancer/Indexbychrom/idx_11.html
    ePath CGAP Mitelman Database of Chromosome Aberrations in Cancer http://cgap.nci.nih.gov/Chromosomes/Mitelman
    ePath Ensembl Human Map View http://www.ensembl.org/perl/mapview?chr=11
    ePath Genew: Human Gene Nomenclature Database Search Engine Approved names and symbols for human genes, together with aliases and previous symbols http://www.gene.ucl.ac.uk/cgi-bin/nomenclature/searchgenes.pl
    ePath Genome Database http://www.gdb.org
    ePath Human Genome Browser Gateway (Golden Path version 029) http://genome.ucsc.edu/cgi-bin/hgGateway?db=hg7
    ePath Jackson Laboratory Mouse Genome Informatics http://www.informatics.jax.org/
    ePath Marshfiled Clinic, Center for Medical Genetics http://www.marshfieldclinic.org/research/genetics/Map_Markers/maps/IndexMapFrames.html
    ePath NCBI Human–Mouse Homology Map http://www.ncbi.nlm.nih.gov/Homology/
    ePath NCBI LocusLink http://www.ncbi.nlm.nih.gov/LocusLink/
    ePath NCBI UniGene http://www.ncbi.nlm.nih.gov/UniGene/
    ePath Online Mendelian Inheritance in Man (OMIM) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM
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How to Cite close
Gerhard, Daniela S(Jan 2006) Chromosome 11. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005820]