Abstract
Human chromosome 11 is a submetacentric chromosome that contains some 4% of the genome and a number of imprinted genes.
Keywords: chromosome 11; sequencing; imprinting; translocations; diseases
Daniela S Gerhard, Office of Cancer Genomics, NCI, Bethesda, Maryland, USA
Published online: January 2006
DOI: 10.1038/npg.els.0005820
Human chromosome 11 is a submetacentric chromosome that contains some 4% of the genome and a number of imprinted genes.
Keywords: chromosome 11; sequencing; imprinting; translocations; diseases
References
Broman KW, Murray JC, Sheffield VC, White RL and Weber JL (1998) Comprehensive human genetic maps: individual and sex‐specific variation in recombination. American Journal of Human Genetics 63: 861–869.
Further Reading
Gaudray P, et al. (1999) Report on the Sixth International Workshop on Human Chromosome 11 Mapping 1998. Cyto‐genetics and Cell Genetics 86: 167–186.
International Genome Sequencing Consortium (2001) Initial sequencing and analysis of the human genome. Nature 409: 860–921.
James MR, Richard 3rd CW, Schott JJ, et al. (1994) A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nature Genetics 8: 70–76.
Maher ER and Reik W (2000) Beckwith–Wiedemann syndrome: imprinting in clusters revisited. Journal of Clinical Investigation 105: 247–252.
Yu A, Zhao C, Fan Y, et al. (2001) Comparison of human genetic and sequence‐based physical maps. Nature 409: 951–953.
Zhang J, Qin S, Sait SNJ, et al. (2001) The pericentromeric region of human chromosome 11: evidence for a chromosome‐specific duplication. Cytogenetics and Cell Genetics 94: 137–141.
Web Links
Atlas of Genetics and Cytogenetics in Oncology and Haematology. http://www.infobiogen.fr/services/chromcancer/Indexbychrom/idx_11.html
CGAP Mitelman Database of Chromosome Aberrations in Cancer http://cgap.nci.nih.gov/Chromosomes/Mitelman
Ensembl Human Map View http://www.ensembl.org/perl/mapview?chr=11
Genew: Human Gene Nomenclature Database Search Engine Approved names and symbols for human genes, together with aliases and previous symbols http://www.gene.ucl.ac.uk/cgi‐bin/nomenclature/searchgenes.pl
Genome Database http://www.gdb.org
Human Genome Browser Gateway (Golden Path version 029) http://genome.ucsc.edu/cgi‐bin/hgGateway?db=hg7
Jackson Laboratory Mouse Genome Informatics http://www.informatics.jax.org/
Marshfiled Clinic, Center for Medical Genetics http://www.marshfieldclinic.org/research/genetics/Map_Markers/maps/IndexMapFrames.html
NCBI Human–Mouse Homology Map http://www.ncbi.nlm.nih.gov/Homology/
NCBI LocusLink http://www.ncbi.nlm.nih.gov/LocusLink/
NCBI UniGene http://www.ncbi.nlm.nih.gov/UniGene/
Online Mendelian Inheritance in Man (OMIM) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM