Chromosome 13

Abstract

Human chromosome 13 is an acrocentric chromosome that contains 3.6% of the genetic material in the genome. It contains a rRNA gene cluster but appears to be relatively gene‐poor.

Keywords: acrocentric chromosome; genomic sequence; disease genes

Figure 1.

Chromosome 13 stained with Giemsa showing the distinctive banding pattern. The dark bands correspond to regions of the chromosome with a low GC content.

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References

Gregory SG, Sekhon M and Schein J (2002) Physical map of the mouse genome. Nature 418: 743–750.

Morton NE (1991) Parameters of the human genome. Proceedings of the National Academy of Sciences of the United States of America 88: 7474–7476.

Pavlicek A, Paces J, Clay O and Bernardi G (2002) A compact view of isochores on the draft genome sequence. FEBS Letters 511: 165–169.

Web Links

Ensembl http://www.ensembl.org

Genew: Human Gene Nomenclature Database Search Engine http://www.gene.ucl.ac.uk/cgi‐bin/nomenclature/searchgenes.pl

Human Chromosome 13 Project Overview http://www.sanger.ac.uk/HGP/Chr13/

LocusLink http://www.ncbi.nlm.nih.gov/LocusLink/

National Center for Biotechnology Information (NCBI) http://www.ncbi.nlm.nih.gov/

Online Mendelian Inheritance in Man (OMIM) http://www.ncbi.nlm.nih.gov/Omim/

5‐Hydroxytryptamine (serotonin) receptor 2A (HTR2A); LocusID: 3356. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=3356

ATPase, Cu2+ transporting, beta polypeptide (ATP7B); LocusID: 540. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=540

Breast cancer 2, early onset (BRCA2). LocusID: 675. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=675

Retinoblastoma 1 (RB1). LocusID: 5925. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=5925

5‐Hydroxytryptamine (serotonin) receptor 2A (HTR2A); MIM number: 182135. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?5925

ATPase, Cu2+ transporting, beta polypeptide (ATP7B); MIM number: 606882. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?

Breast cancer 2, early onset (BRCA2). MIM number: 600185. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?600185

Retinoblastoma 1 (RB1). MIM number: 180200. OMIM: http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/dispmim?180200

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How to Cite close
Dunham, Andrew(Jan 2006) Chromosome 13. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005822]