Chromosome 18

Abstract

Human chromosome 18 is a submetacentric chromosome containing 2–6% of the genetic material in the genome. It is relatively gene poor.

Keywords: chromosome 18; sequences; genes; syndromes; disorders; cancer

References

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Further Reading

Silverman GA and Overhauser J (1995) Human chromosome 18, genetic and physical map status. In: Meyers RA (ed.) Encyclopedia of Molecular Biology and Molecular Medicine, pp. 190–215. New York, NY: VCH.

Web Links

Cancer Genome Anatomy Project. BACs mapped to chromosome 18 by FISH http://cgap.nci.nih.gov/Chromosomes/BAC_Clone_Map?CHR=18

Cancer Genome Anatomy Project. Recurrent chromosome abnormalities in cancer http://cgap.nci.nih.gov/Chromosomes/RecurrentAberrations

Celera. Chromosome 18 sequencing http://www.celera.com

Center for Medical Genetics. Marshfield genetic map http://research.marshfieldclinic.org/genetics/Map_Markers/maps/IndexMapFrames.html

CEPH/Genethon. Genetic map http://www.cephb.fr/ceph‐genethon‐map.html

CHLC genetic map http://gai.nci.nih.gov/cgi‐bin/selectchrom?chromosome=Chromosome+18&reference=v4.chlc.v2.skel

EMBL‐EBI Genome Monitoring Table. Daily updates on pace of genomic sequencing http://www.ebi.ac.uk/genomes/mot

Ensembl. Chromosome 18 sequencing http://www.ensembl.org/Homo_sapiens/mapview?chr=18

Gene gateway – exploring genes and genetic disorders. Disease related genes http://www.ornl.gov/hgmis/posters/chromosome/chromo18.html

HUGO. General information http://www.gdb.org/hugo/chr18

Molecular Genetics Laboratories of Julie R. Korenberg. BACs mapped to chromosome 18 by FISH http://www.csmc.edu/genetics/korenberg/bac‐sts/ch18.jpg

NCBI. Human–mouse homology http://www.ncbi.nlm.nih.gov/Homology/

NCBI GeneMap '98. Radiation hybrid map http://www.ncbi.nlm.nih.gov/genemap98

NCBI Genome Sequencing. Chromosome 18 sequencing http://www.ncbi.nlm.nih.gov/genome/seq/

NCBI Unigene. Unigene gene and EST collection http://www.ncbi.nlm.nih.gov/UniGene/Hs_DATA/ChromLists/Chr18.html

OMIM. Disease related genes http://www.ncbi.nlm.nih.gov/htbin‐post/Omim/getmap?chromosome=18&first=+Find+&start=‐2

OMIM Database http://www.ncbi.nim.nih.gov/htbin‐post/omim

SNP Consortium Ltd. SNP maps http://snp.cshl.org

UCSC Genome Bioinformatics. Chromosome 18 sequencing http://www.genome.ucsc.edu

Whitehead Institute/MIT Center for Genome Research. YAC based contig maps http://www‐genome.wi.mit.edu/cgi‐bin/contig/yac_info

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How to Cite close
van Kessel, Ad Geurts, and Silverman, Gary(Jan 2006) Chromosome 18. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005827]