Gene therapy can be defined as the deliberate transfer of genetic material for a therapeutic purpose.
Keywords: gene therapy; cancer; germ line; transcription; ethics
Gene Therapy
Karol Sikora, Imperial College, Hammersmith Hospital, London, UK
Published online: January 2006
DOI: 10.1038/npg.els.0005835
| Further Reading | |
| Bolognani F and Goya RG (2001) Gene therapy in the neuroendocrine system. Neuroendocrinology 73: 75–83. | |
| Chuah MK, Collen D and Vandendriessche T (2001) Gene therapy for haemophilia. Journal of Gene Medicine 3: 3–20. | |
| Jenks S (2000) Gene therapy death – everyone has to share in the guilt. Journal of the National Cancer Institute 92: 98–100. | |
| book Kresina T (ed.) (2001) An Introduction to Molecular Medicine and Gene Therapy New York, NY: Wiley-Liss. | |
| Morgan RA (1999) Genetic strategies to inhibit HIV. Molecular Medicine Today 5: 454–458. | |
| Morgan RA and Blaese RM (1999) Gene therapy: lessons learnt from the last decade. British Medical Journal 319: 1310. | |
| Pouton CW and Seymour LW (2001) Key issues in non viral gene delivery. Advanced Drug Delivery Reviews 46: 187–203. | |
| Robinson HL (1999) DNA vaccines: basic mechanism and immune responses. International Journal of Molecular Medicine 4: 549–555. | |
| Stephenson J (2000) Gene therapy trial shows clinical efficacy. Journal of the American Medical Association 283: 589–590. | |
| Zanjani ED and Anderson WF (1999) Prospects for in utero human gene therapy. Science 285: 2084–2088. | |
| Web Links | |
| ePath Adenosine deaminase (ADA); MIM number: 102700. OMIM: http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?102700 | |
| ePath Adenosine deaminase (ADA); LocusID: 100. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=100 | |
| ePath Cystic fibrosis transmembrane conductance regulator (CFTR); MIM number: 602421. OMIM: http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?602421 | |
| ePath Cystic fibrosis transmembrane conductance regulator (CFTR); LocusID: 1080. LocusLink: http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=1080 | |
