Genetic Disorders in History and Prehistory


The historical aspects of genetic disorders are deduced from analysis of modern cases. Direct studies of DNA from ancient human remains could become integrated with this approach if a number of difficult technical problems can be solved.

Keywords: genetic disorder; ancient DNA; human migration; disease concept; historical perspective


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Further Reading

Goldstein DB and Chikhi L (2002) Human migrations and population structure: what we know and why it matters. Annual Review of Genomics and Human Genetics 3: 129–152.

O'Rourke DH, Hayes MG and Carlyle SW (2000) Ancient DNA studies in physical anthropology. Annual Review of Anthropology 29: 217–242.

Templeton AR (2002) Out of Africa again and again. Nature 416: 45–51.

Web Links

Hemochromatosis (HFE); LocusID: 3077. LocusLink:

Cystic fibrosis transmembrane conductance regulator, ATP‐binding cassette (CFTR); LocusID: 1080. LocusLink:

Hemochromatosis (HFE); MIM number: 235200. OMIM:‐post/Omim/dispmim?235200

Cystic fibrosis transmembrane conductance regulator, ATP‐binding cassette (CFTR); MIM number: 602421. OMIM:‐post/Omim/dispmim?602421

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How to Cite close
Nielsen, Henrik(Sep 2006) Genetic Disorders in History and Prehistory. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0005880]