References
Akhtar A and
Gasser SM
(2007)
The nuclear envelope and transcriptional control.
Nature Reviews. Genetics
8(7):
507–517.
Blobel G
(1985)
Gene gating: a hypothesis.
Proceedings of the National Academy of Sciences of the USA
82(24):
8527–8529.
Carmody SR and
Wente SR
(2009)
mRNA nuclear export at a glance.
Journal of Cell Science
122(12):
1933–1937.
Cremer T and
Cremer C
(2001)
Chromosome territories, nuclear architecture and gene regulation in mammalian cells.
Nature Reviews. Genetics
2(4):
292–301.
Dirks RW,
Hattinger CM,
Molenaar C and
Snaar SP
(1999)
Synthesis, processing, and transport of RNA within the three‐dimensional context of the cell nucleus.
Critical Reviews in Eukaryotic Gene Expression
9(3–4):
191–201.
Dworetzky SI and
Feldherr CM
(1988)
Translocation of RNA‐coated gold particles through the nuclear pores of oocytes.
Journal of Cell Biology
106(3):
575–584.
Iglesias N and
Stutz F
(2008)
Regulation of mRNP dynamics along the export pathway.
FEBS Letters
582(14):
1987–1996.
Janicki SM,
Tsukamoto T,
Salghetti SE et al.
(2004)
From silencing to gene expression: real‐time analysis in single cells.
Cell
116(5):
683–698.
Kohler A and
Hurt E
(2007)
Exporting RNA from the nucleus to the cytoplasm.
Nature Reviews. Molecular Cell Biology
8(10):
761–773.
Kumaran RI,
Thakar R and
Spector DL
(2008)
Chromatin dynamics and gene positioning.
Cell
132(6):
929–934.
Kylberg K,
Bjork P,
Fomproix N et al.
(2010)
Exclusion of mRNPs and ribosomal particles from a thin zone beneath the nuclear envelope revealed upon inhibition of transport.
Experimental Cell Research
316(6):
1028–1038.
Mor A,
Suliman S,
Ben‐Yishay R et al.
(2010)
Dynamics of single mRNP nucleocytoplasmic transport and export through the nuclear pore in living cells.
Nature Cell Biology
12(6):
543–552.
Politz JC,
Browne E,
Wolf D and
Pederson T
(1998)
Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells.
Proceedings of the National Academy of Sciences of the USA
95(11):
6043–6048.
Politz JC,
Tuft RA,
Pederson T and
Singer RH
(1999)
Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells.
Current Biology
9(6):
285–291.
Politz JC,
Tuft RA,
Prasanth KV et al.
(2006)
Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm.
Molecular Biology of the Cell
17(3):
1239–1249.
Ragoczy T,
Bender MA,
Telling A,
Byron R and
Groudine M
(2006)
The locus control region is required for association of the murine beta‐globin locus with engaged transcription factories during erythroid maturation.
Genes & Development
20(11):
1447–1457.
Shav‐Tal Y,
Darzacq X,
Shenoy SM et al.
(2004)
Dynamics of single mRNPs in nuclei of living cells.
Science
304(5678):
1797–1800.
Siebrasse JP,
Veith R,
Dobay A et al.
(2008)
Discontinuous movement of mRNP particles in nucleoplasmic regions devoid of chromatin.
Proceedings of the National Academy of Sciences of the USA
105(51):
20291–20296.
Singh OP,
Björkroth B,
Masich S,
Wieslander L and
Daneholt B
(1999)
The intranuclear movement of Balbiani ring premessenger ribonucleoprotein particles.
Experimental Cell Research
251(1):
135–146.
Sutherland H and
Bickmore WA
(2009)
Transcription factories: gene expression in unions?
Nature Reviews. Genetics
10(7):
457–466.
Vargas DY,
Raj A,
Marras SA,
Kramer FR and
Tyagi S
(2005)
Mechanism of mRNA transport in the nucleus.
Proceedings of the National Academy of Sciences of the USA
102(47):
17008–17013.
Zachar Z,
Kramer J,
Mims IP and
Bingham PM
(1993)
Evidence for channeled diffusion of pre‐mRNAs during nuclear RNA transport in metazoans.
Journal of Cell Biology
121(4):
729–742.
Zhao J,
Jin S‐B,
Björkroth B,
Wieslander L and
Daneholt B
(2002)
The mRNA export factor Dbp5 is associated with Balbiani ring mRNP from gene to cytoplasm.
EMBO Journal
21(5):
1177–1187.
Further Reading
van den Bogaard PT and
Tyagi S
(2009)
Using molecular beacons to study dispersal of mRNPs from the gene locus.
Methods in Molecular Biology
464:
91–103.
Daneholt B
(2001)
Assembly and transport of a premessenger RNP particle.
Proceedings of the National Academy of Sciences of the USA
98(13):
7012–7017.
Jackson DA,
Pombo A and
Iborra F
(2000)
The balance sheet for transcription: an analysis of nuclear RNA metabolism in mammalian cells.
FASEB Journal
14(2):
242–252.
Moore MJ and
Proudfoot NJ
(2009)
Pre‐mRNA processing reaches back to transcription and ahead to translation.
Cell
136(4):
688–700.
Park HY,
Buxbaum AR and
Singer RH
(2010)
Single mRNA tracking in live cells.
In: Methods in Enzymology: Single Molecule Tools, Pt A: Fluorescence Based Approaches,
vol 472,
pp. 387–406.
San Diego: Elsevier Academic Press Inc.
Pederson T
(2010)
The nucleus introduced.
In: Spector D and
Misteli T (eds)
Cold Spring Harbor Perspectives in Biology.
New York: Cold Spring Harbor Laboratory Press.
Politz JC and
Pederson T
(2000)
Movement of mRNA from transcription site to nuclear pores.
Journal of Structural Biology
129(2–3):
252–257.
Schuss Z,
Singer A and
Holcman D
(2007)
The narrow escape problem for diffusion in cellular microdomains.
Proceedings of the National Academy of Sciences of the USA
104(41):
16098–16103.
Vinciguerra P and
Stutz F
(2004)
mRNA export: an assembly line from genes to nuclear pores.
Current Opinion in Cell Biology
16(3):
285–292.
Wachsmuth M,
Waldeck W and
Langowski J
(2000)
Anomalous diffusion of fluorescent probes inside living cell nuclei investigated by spatially resolved fluorescence correlation spectroscopy.
Journal of Molecular Biology
298(4):
677–689.