John Stanley Mattick, University of Queensland, Brisbane, Australia
Published online: January 2006
DOI: 10.1038/npg.els.0005985
Around 97–98% of the transcriptional output of the human genome is noncoding RNA, which is derived from noncoding RNA genes and from introns in protein‐coding genes. These RNAs may form a higher‐order regulatory network that integrates complex suites of gene activity during differentiation and development.
Keywords: introns; eRNA; RNA interference; intergenic; processing
References
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Further Reading
Akhtar A, Zink D and Becker PB (2000) Chromodomains are protein–RNA interaction modules. Nature 407: 405–409.
van Hoof A and Parker R (1999) The exosome: a proteasome for RNA? Cell 99: 347–350.
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