Exonic Splicing Enhancers

Abstract

Exonic splicing enhancers (ESEs) are short motifs in exons that promote both constitutive and alternative splicing. Several splicing factors, known as SR proteins, bind specifically to ESEs during the initial steps of splicing to initiate assembly of the spliceosomal complex.

Keywords: alternative splicing; exon; intron; sequence motif; enhancer

References

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How to Cite close
Fedorov, Alexei, and Fedorova, Larisa(Jan 2006) Exonic Splicing Enhancers. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0006153]