Molecular Entry Point: Strategies in Proteomics


The term proteomics broadly encompasses the characterization of protein expression, structure and function in a global fashion. The breadth of applications requires an equally diverse array of tools and techniques that address these applications.

Keywords: proteomics; profiling; interaction; crystallography; mass spectrometry; surface‐enhanced laser desorption/ionization; phosphorylation; array


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Further Reading

Baxevanis A and Ouellette B (2001) Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. New York, NY: Wiley‐Liss.

Graves PR and Haystead TAJ (2002) Molecular biologist's guide to proteomics. Microbiology and Molecular Biology Reviews 66: 39–63.

Petricoin EF, Zoon KC, Kohn EC, Barrett JC and Liotta LA (2002) Clinical proteomics: translating benchside promise into bedside reality. Nature Drug Discovery 1: 683–695.

Yarmush ML and Jayaraman A (2002) Advances in proteomic technologies. Annual Review of Biomedical Engineering 4: 349–373.

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Fung, Eric T(Jan 2006) Molecular Entry Point: Strategies in Proteomics. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0006185]