Bacterial Proteomes

Abstract

Proteomes represent the composition of the functional information‐containing macromolecules (proteins) of an organism or a defined part of it. A global view of bacterial proteomes will illuminate basic biological principles such as the functioning of a cell and the elucidation of pathological important proteins for vaccine development, diagnosis and therapy of infectious diseases. Understanding of bacterial proteomes will illuminate basic biological principles such as the functioning of a cell and will allow the elucidation of pathological important proteins for vaccine development, diagnosis and therapy of infectious diseases.

References

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Further Reading

Bumann D, Meyer TF and Jungblut PR (2001) Proteome analysis of the common human pathogen Helicobacter pylori. Proteomics 1: 473–479.

Cordwell SJ, Nouwens AS and Walsh BJ (2001) Comparative proteomics of bacterial pathogens. Proteomics 1: 461–472.

Jungblut PR (2001) Proteome analysis of bacterial pathogens. Microbes and Infection 3: 831–840.

Neidhardt FC and Savageau MA (1996) Regulation beyond the operon In: Neidhardt FC, Curtiss R, Ingraham JL, et al. (eds.), Escherichia coli and Salmonella: Cellular and Molecular Biology, pp. sss1310–1324. Washington DC: ASM Press.

Jungblut PR (guest ed.) (2001) Infectious diseases (Special Issue) Proteomics 1(4), pp. 459–632. Germany: Wiley/Weinheim.

Rosenkrands I, King A, Weldingh K, et al. (2000) Towards the proteome of Mycobacterium tuberculosis. Electrophoresis 21: 3740–3756.

Web Links

2D‐PAGE database. Mycobacterium release 4, 2002; Helicobacter release 3, 2002. http://www.mpiib‐berlin.mpg.de/2D‐PAGE/

BioCyc Knowledge Library. BioCyc is a collection of pathway/genome databases http://biocyc.org/

Kyoto Encyclopedia of Genes and Genomes (KEGG). KEGG is a suite of databases and associated software integrating our current knowledge on molecular interaction networks in biological processes, the information about the universe of genes and proteins and the information about the universe of chemical compounds and reactions http://www.genome.ad.jp/kegg/

Protein Extraction Description and Analysis Tool (PEDANT). PEDANT is a software system for completely automatic and exhaustive analysis of protein sequence sets – from individual sequences to complete genomes http://pedant.gsf.de/

Proteome 2D‐PAGE database. This page contains several bacterial proteomes. Mass spectrometry data, functional classification and protein annotation data may be searched http://www.mpiib‐berlin.mpg.de/2D‐PAGE

TIGR Microbial Database. A listing of published microbial genomes and chromosomes and those in progress http://www.tigr.org/tdb/mdb/mdbcomplete.html

WORLD‐2DPAGE. This page contains references to known 2‐DPAGEdatabase servers, as well as to 2‐D PAGE related servers and services http://www.expasy.ch/ch2d‐index.html

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How to Cite close
Jungblut, Peter R(Jan 2006) Bacterial Proteomes. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0006186]