Protein Structure Prediction and Databases

Francisco S Domingues, Max‐Planck Institute for Informatics, Saarbr¨cken, Germany
Thomas Lengauer, Max‐Planck Institute for Informatics, Saarbr¨cken, Germany
Ingolf Sommer, Max‐Planck Institute for Informatics, Saarbr¨cken, Germany

Published online: September 2006

DOI: 10.1002/9780470015902.a0006214

Three-dimensional structures of proteins are the key to their molecular function. Traditionally protein structures are determined by experiment. The large set of protein sequences that become available through genomics or proteomics activities calls for computer support of protein structure prediction. Today several databases complement the comparatively small set of protein structures measured by experiment with much larger sets of protein models generated by computer.

Keywords: protein structure; protein structure prediction; protein structure databases; structural genomics; Swiss-model; MODBASE

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 Web Links
    ePath CAFASP. Critical assessment of fully automated structure prediction http://www.cs.bgu.ac.il/~dfischer/CAFASP3/
    ePath ModBase. A database of comparative protein structure models http://alto.rockefeller.edu/modbase-cgi/index.cgi
    ePath Pfam: Protein Families database, includes structural models predicted by ab initio http://www.sanger.ac.uk/Software/Pfam/index.shtml

Related Sub-Topics:

Protein Structure | Bioinformatics | Posttranslational Modification | Techniques and Tools in Molecular Biology | Computational Molecular Biology | Proteins: Structure, Function, Metabolism
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Article Title: Protein Structure Prediction and Databases
 
How to Cite close
Domingues, Francisco S, Lengauer, Thomas, and Sommer, Ingolf(Sep 2006) Protein Structure Prediction and Databases. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0006214]