Genetic Maps: Direct Meiotic Analysis
Maj Hultén, University of Warwick, Coventry, UK
Charles Tease, University of Warwick, Coventry, UK
Published online: September 2006
DOI: 10.1002/9780470015902.a0006250
Abstract
Cytogenetic analyses provide a direct means of obtaining critical information on the patterns of meiotic recombination, at
the genomic and chromosome‐specific levels, in both male and female germ cells. This information provides insight into the
control of meiotic recombination in human germ cells and allows the construction of accurate sex‐specific genetic maps.
Keywords: genetic recombination map; crossing‐over; chiasmata; MLH1 foci; spermatocytes; oocytes
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