Casey H Halpern, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Howard I Hurtig, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Gordon H Baltuch, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Published online: April 2007
DOI: 10.1038/9780470015902.a0020283
Deep brain stimulation (DBS) is an effective surgical therapy for well-selected patients with advanced Parkinson disease and essential tremor. DBS may also offer promise for other neurological diseases, such as dystonia, Tourette Syndrome and epilepsy.
Keywords: deep brain stimulation; Parkinson disease; movement disorder; epilepsy; depression
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| Further Reading | |
| book Baltuch GH and Stern MB (2005) Surgical Management of Movement Disorders, Boca Raton: Taylor and Francis Group pp. 1–311. | |
| Broggi G, Franzini A, Marras C, Romito L and Albanese A (2003) Surgery of Parkinson's disease: inclusion criteria and follow-up. Neurological Sciences. 24 (Suppl. 1): S38–S40. | |
| Gross RE (2004) Deep brain stimulation in the treatment of neurological and psychiatric Disease. Expert Review of Neurotherapeutics. 4(3): 465–478. | |
| other Halpern C, Hurtig H, Jaggi J et al. (2006) Parkinsonism and related disorders. [Epub ahead of print]. | |
| Kleiner-Fisman G, Herzog J, Fisman DN et al. (2006) Subthalamic nucleus deep brain stimulation: summary and meta-analysis of outcomes. Movement Disorders 21 (Suppl 14): S290–S304. | |
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| Romanelli P, Bronte-Stewart H, Heit G, Schaal DW and Esposito V (2004) The functional organization of the sensorimotor region of the subthalamic nucleus. Stereotactic and Functional Neurosurgery 82(5–6): 222–229. | |
| Temel Y and Visser-Vandewalle V (2006) Targets for deep brain stimulation in Parkinson's Disease. Expert Opinion on Therapeutic Targets 10(3): 355–362. | |
| Walter BL and Vitek JL (2004) Surgical treatment for Parkinson's disease. Lancet Neurology 3(12): 719–728. | |
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