Yasuhiro Takeuchi, University College London, London, UK
Giada Mattiuzzo, University College London, London, UK
Published online: December 2007
DOI: 10.1002/9780470015902.a0020708
Xenotransplantation using genetically modified pigs may become a clinical reality in the near future and help many patients with various medical conditions. The study of porcine viruses is essential to delineate the potential risk of xenotransplantation-mediated zoonoses.
Keywords: porcine viruses; safety; transgenic pigs; xenotransplantation; zoonosis
| References | |
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| Further Reading | |
| Deschamps J-Y, Roux FA, Saï P and Gouin E (2005) History of xenotransplantation. Xenotransplantation 12: 91–109. | |
| Fishman JA and Patience C (2004) Xenotransplantation: infectious risk revisited. American Journal of Transplantation 4: 1383–1390. | |
| Lu L, Li C and Hagedorn CH (2006) Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Reviews of Medical Virology 16: 5–36. | |
| Magre S, Takeuchi Y and Bartosch B (2003) Xenotransplantation and pig endogenous retrovirus. Reviews in Medical Virology 13: 311–329. | |
| other Salomon DR and Wilson C (eds) (2003) Xenotransplantation. Current Topics in Microbiology and Immunology 278, Springer, Germany. | |
| Smetanka C and Cooper DKC (2005) The ethics debate in relation to xenotransplantation. Revue scientifique et technique (International Office of Epizootics) 24: 335–342. | |
| Wong S, Lau S, Woo P and Yuen K-Y (2007) Bats as a continuing source of emerging infections in humans. Reviews in Medical Virology 17: 67–91. | |
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