| References |
|
|
Anderson JS and
Parker RP
(1998)
The 3′ to 5′ degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3′ to 5′ exonucleases of the exosome complex.
EMBO Journal
17:
1497–1506.
|
|
|
Araki Y,
Takahashi S,
Kobayashi T et al.
(2001)
Ski7p G protein interacts with the exosome and the Ski complex for 3′‐to‐5′ mRNA decay in yeast.
EMBO Journal
20:
4684–4693.
|
|
|
Arigo JT,
Eyler DE,
Carroll KL and
Corden JL
(2006)
Termination of cryptic unstable transcripts is directed by yeast RNA‐binding proteins Nrd1 and Nab3.
Molecular Cell
23:
841–851.
|
|
|
Azzouz N,
Panasenko OO,
Colau G and
Collart MA
(2009)
The CCR4‐NOT complex physically and functionally interacts with TRAMP and the nuclear exosome.
PloS One
4:
e6760.
|
|
|
Basu U,
Meng FL,
Keim C et al.
(2011)
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.
Cell
144:
353–363.
|
|
|
Belostotsky D
(2009)
Exosome complex and pervasive transcription in eukaryotic genomes.
Current Opinion in Cell Biology
21:
352–358.
|
|
|
Bonneau F,
Basquin J,
Ebert J,
Lorentzen E and
Conti E
(2009)
The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation.
Cell
139:
547–559.
|
|
|
Briggs MW,
Burkard KT and
Butler JS
(1998)
Rrp6p, the yeast homologue of the human PM‐Scl 100‐kDa autoantigen, is essential for efficient 5.8 S rRNA 3′ end formation.
Journal of Biological Chemistry
273:
13255–13263.
|
|
|
Brouwer R,
Pruijn GJ and
van Venrooij WJ
(2001)
The human exosome: an autoantigenic complex of exoribonucleases in myositis and scleroderma.
Arthritis Research
3:
102–106.
|
|
|
Burkard KT and
Butler JS
(2000)
A nuclear 3′‐5′ exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p.
Molecular and Cellular Biology
20:
604–616.
|
|
|
Butler JS and
Mitchell P
(2010)
Rrp6, Rrp47 and cofactors of the nuclear exosome.
Advances in Experimental Medicine and Biology
702:
91–104.
|
|
|
Chapman MA,
Lawrence MS,
Keats JJ et al.
(2011)
Initial genome sequencing and analysis of multiple myeloma.
Nature
471:
467–472.
|
|
|
Chekanova JA,
Shaw RJ,
Wills MA and
Belostotsky DA
(2000)
Poly(A) tail‐dependent exonuclease AtRrp41p from Arabidopsis thaliana rescues 5.8 S rRNA processing and mRNA decay defects of the yeast ski6 mutant and is found in an exosome‐sized complex in plant and yeast cells.
Journal of Biological Chemistry
275:
33158–33166.
|
|
|
Chen CY,
Gherzi R,
Ong SE et al.
(2001)
AU binding proteins recruit the exosome to degrade ARE‐containing mRNAs.
Cell
107:
451–464.
|
|
|
Cristodero M,
Bottcher B,
Diepholz M,
Scheffzek K and
Clayton C
(2008)
The Leishmania tarentolae exosome: purification and structural analysis by electron microscopy.
Molecular and Biochemical Parasitology
159:
24–29.
|
|
|
Doma MK and
Parker R
(2006)
Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation.
Nature
440:
561–564.
|
|
|
Dziembowski A,
Lorentzen E,
Conti E and
Seraphin B
(2007)
A single subunit, Dis3, is essentially responsible for yeast exosome core activity.
Nature Structural & Molecular Biology
14:
15–22.
|
|
|
Eberle AB,
Lykke‐Andersen S,
Muhlemann O and
Jensen TH
(2009)
SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells.
Nature Structural & Molecular Biology
16:
49–55.
|
|
|
Evguenieva‐Hackenberg E,
Walter P,
Hochleitner E,
Lottspeich F and
Klug G
(2003)
An exosome‐like complex in Sulfolobus solfataricus.
EMBO Reports
4:
889–893.
|
|
|
Frazao C,
McVey CE,
Amblar M et al.
(2006)
Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA‐bound complex.
Nature
443:
110–114.
|
|
|
Grzechnik P and
Kufel J
(2008)
Polyadenylation linked to transcription termination directs the processing of snoRNA precursors in yeast.
Molecular Cell
32:
247–258.
|
|
|
Guo X,
Ma J,
Sun J and
Gao G
(2007)
The zinc‐finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA.
Proceedings of the National Academy of Sciences of the USA
104:
151–156.
|
|
|
Hartung S,
Niederberger T,
Hartung M,
Tresch A and
Hopfner KP
(2010)
Quantitative analysis of processive RNA degradation by the archaeal RNA exosome.
Nucleic Acids Research
38:
5166–5176.
|
|
|
van Hoof A,
Lennertz P and
Parker R
(2000)
Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast.
EMBO Journal
19:
1357–1365.
|
|
|
Houseley J,
LaCava J and
Tollervey D
(2006)
RNA‐quality control by the exosome.
Nature Reviews Molecular Cell Biology
7:
529–539.
|
|
|
Ibrahim H,
Wilusz J and
Wilusz CJ
(2008)
RNA recognition by 3′‐to‐5′ exonucleases: the substrate perspective.
Biochimica et Biophysica Acta
1779:
256–265.
|
|
|
Januszyk K,
Liu Q and
Lima CD
(2011)
Activities of human RRP6 and structure of the human RRP6 catalytic domain.
RNA
17:
1566–1577.
|
|
|
Kiss DL and
Andrulis ED
(2010)
The exozyme model: a continuum of functionally distinct complexes.
RNA
17:
1–13.
|
|
|
Kressler D,
Hurt E and
Bassler J
(2010)
Driving ribosome assembly.
Biochimica et Biophysica Acta
1803:
673–683.
|
|
|
Lange H,
Holec S,
Cognat V et al.
(2008)
Degradation of a polyadenylated rRNA maturation by‐product involves one of the three RRP6‐like proteins in Arabidopsis thaliana.
Molecular and Cellular Biology
28:
3038–3044.
|
|
|
Lebreton A,
Tomecki R,
Dziembowski A and
Seraphin B
(2008)
Endonucleolytic RNA cleavage by a eukaryotic exosome.
Nature
456:
993–996.
|
|
|
Liu Q,
Greimann JC and
Lima CD
(2006)
Reconstitution, activities, and structure of the eukaryotic RNA exosome.
Cell
127:
1223–1237.
|
|
|
Lorentzen E,
Basquin J and
Conti E
(2008a)
Structural organization of the RNA‐degrading exosome.
Current Opinion in Structural Biology
18:
709–713.
|
|
|
Lorentzen E,
Basquin J,
Tomecki R,
Dziembowski A and
Conti E
(2008b)
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family.
Molecular Cell
29:
717–728.
|
|
|
Lubas M,
Christensen MS,
Kristiansen MS et al.
(2011)
Interaction profiling identifies the human nuclear exosome targeting complex.
Molecular Cell
43:
624–637.
|
|
|
Lykke‐Andersen S,
Brodersen DE and
Jensen TH
(2009)
Origins and activities of the eukaryotic exosome.
Journal of Cell Science
122:
1487–1494.
|
|
|
Mitchell P,
Petfalski E,
Shevchenko A,
Mann M and
Tollervey D
(1997)
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3′–5′ exoribonucleases.
Cell
91:
457–466.
|
|
|
Mukherjee D,
Gao M,
O'Connor JP et al.
(2002)
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU‐rich elements.
EMBO Journal
21:
165–174.
|
|
|
Orban TI and
Izaurralde E
(2005)
Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome.
RNA
11:
459–469.
|
|
|
Preker P,
Nielsen J,
Kammler S et al.
(2008)
RNA exosome depletion reveals transcription upstream of active human promoters.
Science
322:
1851–1854.
|
|
|
Roppelt V,
Hobel CF,
Albers SV et al.
(2010a)
The archaeal exosome localizes to the membrane.
FEBS Letters
584:
2791–2795.
|
|
|
Roppelt V,
Klug G and
Evguenieva‐Hackenberg E
(2010b)
The evolutionarily conserved subunits Rrp4 and Csl4 confer different substrate specificities to the archaeal exosome.
FEBS Letters
584:
2931–2936.
|
|
|
Schaeffer D,
Tsanova B,
Barbas A et al.
(2009)
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.
Nature Structural & Molecular Biology
16:
56–62.
|
|
|
Schneider C,
Leung E,
Brown J and
Tollervey D
(2009)
The N‐terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome.
Nucleic Acids Research
37:
1127–1140.
|
|
|
Staals RH,
Bronkhorst AW,
Schilders G et al.
(2010)
Dis3‐like 1: a novel exoribonuclease associated with the human exosome.
EMBO Journal
29:
2358–2367.
|
|
|
Stoecklin G,
Mayo T and
Anderson P
(2006)
ARE‐mRNA degradation requires the 5′‐3′ decay pathway.
EMBO Reports
7:
72–77.
|
|
|
Symmons MF,
Jones GH and
Luisi BF
(2000)
A duplicated fold is the structural basis for polynucleotide phosphorylase catalytic activity, processivity, and regulation.
Structure
8:
1215–1226.
|
|
|
Synowsky SA and
Heck AJ
(2008)
The yeast Ski complex is a hetero‐tetramer.
Protein Science
17:
119–125.
|
|
|
Tomecki R,
Kristiansen MS,
Lykke‐Andersen S et al.
(2010)
The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.
EMBO Journal
29:
2342–2357.
|
|
|
Tran H,
Schilling M,
Wirbelauer C,
Hess D and
Nagamine Y
(2004)
Facilitation of mRNA deadenylation and decay by the exosome‐bound, DExH protein RHAU.
Molecular Cell
13:
101–111.
|
|
|
Vasiljeva L and
Buratowski S
(2006)
Nrd1 interacts with the nuclear exosome for 3′ processing of RNA polymerase II transcripts.
Molecular Cell
21:
239–248.
|
|
|
Vincent HA and
Deutscher MP
(2009)
The roles of individual domains of RNase R in substrate binding and exoribonuclease activity. The nuclease domain is sufficient for digestion of structured RNA.
Journal of Biological Chemistry
284:
486–494.
|
|
|
Wyers F,
Rougemaille M,
Badis G et al.
(2005)
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase.
Cell
121:
725–737.
|
|
|
Zuo Y and
Deutscher MP
(2001)
Exoribonuclease superfamilies: structural analysis and phylogenetic distribution.
Nucleic Acids Research
29:
1017–1026.
|
| Further Reading |
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Chlebowski A,
Tomecki R,
Lopez ME,
Seraphin B and
Dziembowski A
(2011)
Catalytic properties of the eukaryotic exosome.
Advances in Experimental Medicine and Biology
702:
63–78.
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Clayton C and
Estevez A
(2011)
The exosomes of trypanosomes and other protists.
Advances in Experimental Medicine and Biology
702:
39–49.
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Coy S and
Vasiljeva L
(2011)
The exosome and heterochromatin: multilevel regulation of gene silencing.
Advances in Experimental Medicine and Biology
702:
105–121.
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|
Evguenieva‐Hackenberg E
(2011)
The archaeal exosome.
Advances in Experimental Medicine and Biology
702:
29–38.
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|
|
Januszyk K and
Lima CD
(2011)
Structural components and architectures of RNA exosomes.
Advances in Experimental Medicine and Biology
702:
9–28.
|
|
|
Lange H and
Gagliardi D
(2011)
The exosome and 3′‐5′ RNA degradation in plants.
Advances in Experimental Medicine and Biology
702:
50–62.
|
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|
Mitchell P and
Tollervey D
(2011)
Finding the exosome.
Advances in Experimental Medicine and Biology
702:
1–8.
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|
Rougemaille M and
Libri D
(2011)
Control of cryptic transcription in eukaryotes.
Advances in Experimental Medicine and Biology
702:
122–131.
|
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|
Schaeffer D,
Clark A,
Klauer AA,
Tsanova B and
van Hoof A
(2011)
Functions of the cytoplasmic exosome.
Advances in Experimental Medicine and Biology
702:
79–90.
|
|
|
Staals RH and
Pruijn GJ
(2011)
The human exosome and disease.
Advances in Experimental Medicine and Biology
702:
132–142.
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