| References |
|
|
Akbar A,
Yiangou Y,
Facer P et al.
(2008)
Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain.
Gut
57(7):
923–929.
|
|
|
Arcogen Consortium
(2012)
Identification of new susceptibility loci for osteoarthritis arcOGEN: a genome-wide association study.
Lancet
380:
815–823.
|
|
|
Belfer I and
Segall S
(2011)
COMT genetic variants and pain.
Drugs of Today
47:
457–467.
|
|
|
Campa D,
Gioia A,
Tomei A,
Poli P and
Barale R
(2007)
Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief.
Clinical Pharmacology and Therapeutics
83(4):
559–566.
|
|
|
Chen J,
Lipska BK,
Halim N et al.
(2004)
Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.
American Journal of Human Genetics
75(5):
807–821.
|
|
|
Cheng KI,
Lin SR,
Chang LL,
Wang JY and
Lai CS
(2010)
Association of the functional A118G polymorphism of OPRM1 in diabetic patients with foot ulcer pain.
Journal of Diabetes and its Complications
24(2):
102–108.
|
|
|
Clay FJ,
Watson WL,
Newstead SV and
McClure RJ
(2012)
A systematic review of early prognostic factors for persistent pain following acute orthopedic trauma.
Pain Research and Management Jan–Feb
17(1):
35–44.
|
|
|
Costigan M,
Belfer I,
Griffin RS et al.
(2010)
Multiple chronic pain states are associated with a common amino acid–changing allele in KCNS1.
Brain
133(9):
2519–2527.
|
|
|
Desmeules J,
Piguet V,
Besson M et al.
(2012)
Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism.
Health Psychology
31(2):
242–249.
|
|
|
Diatchenko L,
Nackley AG,
Slade GD et al.
(2006)
Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli.
Pain
125(3):
216–224.
|
|
|
Diatchenko L,
Nackley AG,
Slade GD,
Fillingim RB and
Maixner W
(2006)
Idiopathic pain disorders? Pathways of vulnerability.
Pain
123(3):
226–230.
|
|
|
Edwards RR
(2006)
Genetic predictors of acute and chronic pain.
Current Rheumatology Reports
8(6):
411–417.
|
|
|
Fernández-de-las-Peñas C,
Ambite-Quesada S,
Gil-Crujera A,
Cigarán-Méndez M and
Peñacoba-Puente C
(2012)
Catechol-O-methyltransferase Val158Met polymorphism influences anxiety, depression, and disability, but not pressure pain sensitivity, in women with fibromyalgia syndrome.
Journal of Pain
13(11):
1068–1074.
|
|
|
Fillingim RB,
Kaplan L,
Staud R et al.
(2005)
The A118G single nucleotide polymorphism of the -opioid receptor gene (oprm1) is associated with pressure pain sensitivity in humans.
Journal of Pain
6(3):
159–167.
|
|
|
Finan PH,
Zautra AJ,
Davis MC et al.
(2011)
COMT moderates the relation of daily maladaptive coping and pain in fibromyalgia.
Pain
152(2):
300–307.
|
|
|
George SZ,
Wallace MR,
Wright TW et al.
(2008)
Evidence for a biopsychosocial influence on shoulder pain: pain catastrophizing and catechol-O-methyltransferase (COMT) diplotype predict clinical pain ratings.
Pain
136(1-2):
53–61.
|
|
|
Herken H,
Erdal E,
Mutlu N et al.
(2001)
Possible association of temporomandibular joint pain and dysfunction with a polymorphism in the serotonin transporter gene.
American Journal of Orthodontics and Dentofacial Orthopedics
120(3):
308–313.
|
|
|
Janicki PK,
Schuler G,
Francis D et al.
(2006)
A genetic association study of the functional A118G polymorphism of the human -opioid receptor gene in patients with acute and chronic pain.
Anesthesia and Analgesia
103(4):
1011–1017.
|
|
|
Kim H,
Neubert JK,
San Miguel A et al.
(2004)
Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament.
Pain
109(3):
488–496.
|
|
|
Kirchheiner J,
Schmidt H,
Tzvetkov M et al.
(2006)
Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.
Pharmacogenomics Journal
7(4):
257–265.
|
|
|
Klengel T,
Heck A,
Pfister H et al.
(2011)
Somatization in major depression – clinical features and genetic associations.
Acta Psychiatrica Scandinavica
124(4):
317–328.
|
|
|
Kolesnikov Y,
Gabovits B,
Levin A,
Voiko E and
Veske A
(2011)
Combined catechol-O-methyltransferase and -opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects.
Anesthesia and Analgesia
112(2):
448–453.
|
|
|
Lee TW,
Yu YW,
Hong CJ et al.
(2011)
The effects of catechol-O-methyl-transferase polymorphism Val158Met on functional connectivity in healthy young females: a resting EEG study.
Brain Research
1377:
21–31.
|
|
|
Liem EB,
Joiner TV,
Tsueda K and
Sessler DI
(2005)
Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads.
Anesthesiology
102(3):
509–514.
|
|
|
Lindstedt F,
Berrebi J,
Greayer E et al.
(2011)
Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene.
PloS One
6(3):
e18252.
|
|
|
Max MB,
Wu T,
Atlas SJ et al.
(2006)
A clinical genetic method to identify mechanisms by which pain causes depression and anxiety.
Molecular Pain
2(1):
1–15.
|
|
|
McKemy DD,
Neuhausser WM and
Julius D
(2002)
Identification of a cold receptor reveals a general role for TRP channels in thermosensation.
Nature
416(6876):
52–58.
|
|
|
Mogil JS,
Ritchie J,
Smith SB et al.
(2005)
Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans.
Journal of Medical Genetics
42:
583–587.
|
|
|
Mogil JS,
Sorge RE,
LaCroix-Fralish ML et al.
(2011)
Pain sensitivity and vasopressin analgesia are mediated by a gene–sex–environment interaction.
Nature Neuroscience
14(12):
1569–1573.
|
|
|
Mogil JS,
Wilson SG,
Bon K et al.
(1999)
Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception.
Pain
80(1):
67–82.
|
|
|
Mogil JS,
Wilson SG,
Chesler EJ et al.
(2003)
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans.
Proceedings of the National Academy of Sciences of the USA
100(8):
4867–4872.
|
|
|
Neely GG,
Hess A,
Costigan M et al.
(2010)
A genome-wide Drosophila screen for heat nociception identifies 23 as an evolutionarily conserved pain gene.
Cell
143(4):
628–638.
|
|
|
Nielsen CS,
Knudsen GP and
Steingrímsdóttir ÓA
(2012)
Twin studies of pain.
Clinical Genetics
82(4):
331–340.
|
|
|
Nielsen CS,
Stubhaug A,
Price DD et al.
(2008)
Individual differences in pain sensitivity: genetic and environmental contributions.
Pain
136(1):
21–29.
|
|
|
Nissenbaum J,
Devor M,
Seltzer ZE et al.
(2010)
Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2.
Genome Research
20(9):
1180–1190.
|
|
|
Ochroch EA,
Vachani A,
Gottschalk A and
Kanetsky PA
(2011)
Natural variation in the -opioid gene OPRM1 predicts increased pain on third day after thoracotomy.
Clinical Journal of Pain
28(9):
747–754.
|
|
|
Oertel B and
Lötsch J
(2008)
Genetic mutations that prevent pain: implications for future pain medication.
Pharmacogenomics
9(2):
179–194.
|
|
|
Oertel BG,
Schmidt R,
Schneider A,
Geisslinger G and
Lötsch J
(2006)
The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers.
Pharmacogenetics and Genomics
16(9):
625–636.
|
|
|
Painter JN,
Anderson CA,
Nyholt DR et al.
(2010)
Genome-wide association study identifies a locus at 7p15. 2 associated with endometriosis.
Nature Genetics
43(1):
51–54.
|
|
|
Park HJ,
Shinn HK,
Ryu SH et al.
(2006)
Genetic polymorphisms in the ABCB1 gene and the effects of fentanyl in Koreans.
Clinical Pharmacology and Therapeutics
81(4):
539–546.
|
|
|
Peters MJ,
Broer L,
Willemen HL et al.
(2012)
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15. 2 region.
Annals of the Rheumatic Diseases
71(9):
1–8.
|
|
|
Rakvåg TT,
Klepstad P,
Baar C et al.
(2005)
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.
Pain
116(1–2):
73–78.
|
|
|
Rakvåg TT,
Ross JR,
Sato H et al.
(2008)
Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain.
Molecular Pain
4(1):
64–76.
|
|
|
Reimann F,
Cox JJ,
Belfer I et al.
(2010)
Pain perception is altered by a nucleotide polymorphism in SCN9A.
Proceedings of the National Academy of Sciences of the USA
107(11):
5148–5153.
|
|
|
Stamer UM and
Stüber F
(2007)
The pharmacogenetics of analgesia.
Expert Opinion on Pharmacotherapy
8:
2235–2245.
|
|
|
Tegeder I,
Costigan M,
Griffin RS et al.
(2006)
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.
Nature Medicine
12(11):
1269–1277.
|
|
|
Wilson SG,
Bryant CD,
Lariviere WR et al.
(2003)
The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice.
Journal of Pharmacology and Experimental Therapeutics
305(2):
755–764.
|
|
|
Xu K,
Ernst M and
Goldman D
(2006)
Imaging genomics applied to anxiety, stress response, and resiliency.
Neuroinformatics
4(1):
51–64.
|
|
|
Young EE,
Lariviere WR and
Belfer I
(2012)
Genetic basis of pain variability: recent advances.
Journal of Medical Genetics
49(1):
1–9.
|
| Further Reading |
|
|
Collins FS,
Brooks LD and
Chakravarti A
(1998)
A DNA polymorphism discovery resource for research on human genetic variation.
Genome Research
8(12):
1229–1231.
|
|
|
Freedman ML,
Reich D,
Penney KL et al.
(2004)
Assessing the impact of population stratification on genetic association studies.
Nature Genetics
36(4):
388–393.
|
|
|
Hirschhorn JN,
Lohmueller K,
Byrne E and
Hirschhorn K
(2002)
A comprehensive review of genetic association studies.
Genetics in Medicine
4(2):
45–61.
|
|
|
LaCroix-Fralish ML and
Mogil JS
(2009)
Progress in genetic studies of pain and analgesia.
Annual Review of Pharmacology and Toxicology
49:
97–121.
|
|
|
Lohmueller KE,
Pearce CL,
Pike M,
Lander ES and
Hirschhorn JN
(2003)
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease.
Nature Genetics
33(2):
177–182.
|
|
|
Lötsch J
(2011)
Genetic variability of pain perception and treatment-clinical pharmacological implications.
European Journal of Clinical Pharmacology
67(6):
541–551.
|
|
|
Mogil JS
(2012)
Pain genetics: past, present and future.
Trends in Genetics
28(6):
258–266.
|
|
|
Schulze TG and
McMahon FJ
(2004)
Defining the phenotype in human genetic studies: forward genetics and reverse phenotyping.
Human Heredity
58(3–4):
131–138.
|
|
|
Smith BH,
Macfarlane GJ and
Torrance N
(2007)
Epidemiology of chronic pain, from the laboratory to the bus stop: time to add understanding of biological mechanisms to the study of risk factors in population-based research.
Pain
127:
5–10.
|
