Forensic Genomics

Abstract

Application of genetics to forensics has been multifactorial, that is analysing various inherited characteristics (genes or gene products) in the same court case. However, only when DNA fast and cheap sequencing technologies became available can we speak of forensic genomics proper, that is the use of genome‐wide data to forensic applications. These advances allow a significant increase in the informative power of classical forensic analyses and open new application avenues that were unthinkable when a reduced amount of genetic markers was at hand. These include the assessment and inference of remote kinship, biogeographic ancestry, and physical appearance. However, these developments still face serious problems, which may be difficult to resolve, or seriously conflict social and individual rights. In fact, full use of forensic genomics face statistical, technical, theoretical, ethical and legal obstacles, which may remain insurmountable in the near future.

Key Concepts

  • Science applied to forensics produces and evaluates evidence in criminal or civil litigations at a formal judicial system.
  • Forensic genetics and genomics are increasingly contributing to the prevention of litigation, alleviating court workloads.
  • Current litigation fields involving genetic expertise are much broader than traditional legal medicine and include the use of nonhuman material.
  • DNA technology has contributed significantly to the expansion and precision of FG.
  • Forensic application of genome‐wide data is loaded with ethical, technical, theoretical and problems.

Keywords: genetics; genomics; forensics; population genetics; DNA

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Further Reading

Amorim A and Budowle B (2016) Handbook of Forensic Genetics: Biodiversity and Heredity in Civil and Criminal Investigation. World Scientific: Hackensack, NJ. DOI: 10.1142/q0023.

Carracedo A (2017) From Hemogenetics to Forensic Genomics. In: Ferrara S (ed.) Medicine and Justice, p P5. Springer: Cham. DOI: 10.1007/978‐3‐319‐67092‐8_28.

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How to Cite close
Amorim, Antonio(Jun 2019) Forensic Genomics. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0026714]