GWAS & Complex Disease
Identification of the genetic variants that influence complex human traits is key to understanding complex disease. Genome-wide association studies (GWAS) have identified some common variants associated with complex disease even though most such variants confer only modest risk. Whilst epidemiological studies are beginning to reveal gene-environment interactions, the advent of next generation sequencing technologies is opening up new possibilities to investigate the etiology of complex disease.
Genome‐wide Association Studies
Chee‐Seng Ku, Yudi Pawitan, Kee‐Seng Chia
Published online: March 2009
Chee‐Seng Ku, Yudi Pawitan, Kee‐Seng Chia
Published online: March 2009
Role of Bioinformatics in Genome‐wide Association Studies
Diane Gilbert‐Diamond, Folkert W Asselbergs, Scott M Williams, Jason H Moore
Published online: October 2011
Diane Gilbert‐Diamond, Folkert W Asselbergs, Scott M Williams, Jason H Moore
Published online: October 2011
Genome‐wide Association Studies: The Success, Failure and Future
Ku Chee‐Seng, Loy En Yun, Pawitan Yudi, Chia Kee‐Seng
Published online: December 2009
Ku Chee‐Seng, Loy En Yun, Pawitan Yudi, Chia Kee‐Seng
Published online: December 2009
Studying Genomic Aberrations by Microarray Profiling
Logan C Walker, Nic Waddell
Published online: April 2010
Logan C Walker, Nic Waddell
Published online: April 2010
Genome‐wide Association Studies of Cancers
Chee Seng Ku, Nasheen Naidoo, Mikael Hartman, Yudi Pawitan
Published online: December 2010
Chee Seng Ku, Nasheen Naidoo, Mikael Hartman, Yudi Pawitan
Published online: December 2010
Genetic Epidemiology of Smoking Behaviour and Nicotine Dependence
Tellervo Korhonen, Jaakko Kaprio
Published online: September 2011
Tellervo Korhonen, Jaakko Kaprio
Published online: September 2011
Molecular Genetics of Tourette Syndrome
Antoinette Valenti, Marco Grados
Published online: January 2012
Antoinette Valenti, Marco Grados
Published online: January 2012
Molecular Genetics of Susceptibility to Coronary Heart Disease
Iftikhar J Kullo, Keyue Ding
Published online: March 2009
Iftikhar J Kullo, Keyue Ding
Published online: March 2009
The Molecular Genetics of Type 2 Diabetes: Past, Present and Future
Jonathan T Tan, Kee Seng Chia, Chee Seng Ku
Published online: December 2009
Jonathan T Tan, Kee Seng Chia, Chee Seng Ku
Published online: December 2009
Molecular Genetics of Coeliac Disease
Vanisha Mistry, David van Heel
Published online: December 2011
Vanisha Mistry, David van Heel
Published online: December 2011
