Neurodegeneration and Neurodegenerative Disorders

A progressive loss in the structure or function of neurons, including neuronal death, termed ‘neurodegeneration’, covers a variety of molecular and cellular processes and result in a number of neurodegenerative diseases, including Huntingdon’s, Alzheimer’s and Parkinson’s diseases. Research, especially on a molecular level, is beginning to reveal similarities in the neurodegenerative process in such diseases, that could lead to improvements in therapeutic approach.


Prions
Victoria A Lawson
Published online: April 2015
Syndromes and Diseases Associated with the Notch Signalling Pathway
Peter D Turnpenny
Published online: August 2014
Gene Therapy for Amyotrophic Lateral Sclerosis
Zachary McEachin, Deirdre O'Connor, Nicholas Boulis
Published online: September 2013
Molecular Genetics of the Neuronal Ceroid Lipofuscinoses
Sara E Mole
Published online: January 2014
Psychoses
Hans W Moises
Published online: October 2013
Nitric Oxide in Human Health and Disease
Sarti Paolo
Published online: April 2013
Molecular Biology of Small Heat Shock Proteins associated with Peripheral Neuropathies
Anne Holmgren, Delphine Bouhy, Vincent Timmerman
Published online: November 2012
Serotonin
Efrain C Azmitia
Published online: October 2012
Mitochondrial Dynamics: Mechanisms and Pathologies
Hakjoo Lee, Yisang Yoon
Published online: June 2012
Genetics of the Autosomal Dominant Spinocerebellar Ataxias
Marc Corral‐Juan, Jordi Corral, Héctor San Nicolás, Victor Volpini, Antoni Matilla‐Dueñas
Published online: October 2011
Pathogenesis of Polyglutamine Diseases
Maria Pennuto, Fabio Sambataro
Published online: December 2010
Genetic Basis of Monogenic Forms of Parkinson Disease
Kathrin Brockmann, Thomas Gasser
Published online: April 2010
Multiple Sclerosis
Jana Preiningerova, Roberto Bomprezzi, Timothy L Vollmer, Stephen G Waxman
Published online: September 2009
The Aetiologic Spectrum of Cerebellar Ataxia: Inherited Causes of Ataxia
Peter K Todd, J Paul Taylor
Published online: March 2009
Neurological Diseases: Gene Therapy
PR Lowenstein, MG Castro
Published online: January 2006