Cell Death

Individual cells face three choices: to divide (mitosis), to specialize (differentiate) or to commit suicide (cell death). Physiological cell death has become a major field of study for cell and molecular biologists in the last twenty years. The articles in this group explain the complex processes involved in the different pathways leading to cell death.


The Origin and Evolution of Programmed Cell Death
Jean Claude Ameisen
Published online: December 2009
Apoptosis: Inherited Disorders
Helen C Su, Michael J Lenardo
Published online: September 2009
Drug Discovery in Apoptosis
Tom O'Brien, Vishva M Dixit
Published online: December 2009
From Reactive Oxygen and Nitrogen Species to Therapy
Scott R McKercher, Tomohiro Nakamura, Stuart A Lipton
Published online: December 2009
Autophagy
María Isabel Colombo, Hans‐Uwe Simon
Published online: December 2009
Autophagy in Nonmammalian Systems
Jahda H Hill, Eric H Baehrecke
Published online: September 2009
Cell Death in C. elegans
Ataman Sendoel, Michael O Hengartner
Published online: December 2009
Caspases and Cell Death
Lorraine D Hernandez, Caroline Houde, Maarten Hoek, Brent Butts, Donald W Nicholson, Huseyin Mehmet
Published online: December 2009
P53 and Cell Death
Kamil Wolyniec, Sue Haupt, Ygal Haupt
Published online: December 2009
Structures, Domains and Functions in Cell Death (DD, DED, CARD, PYD)
Hao Wu, Yu‐Chih Lo
Published online: December 2009
Cornification of the Skin: A Non‐apoptotic Cell Death Mechanism
E Candi, RA Knight, G Melino
Published online: December 2009
Inhibitor of Apoptosis (IAP) and BIR‐containing Proteins
David L Vaux
Published online: September 2009
The BCL‐2 Family Proteins – Key Regulators and Effectors of Apoptosis
David L Vaux
Published online: September 2009
The Apoptosome: The Executioner of Mitochondria‐mediated Apoptosis
Elisabetta Ferraro, Francesco Cecconi
Published online: September 2009
Microbial Inhibitors of Apoptosis
Georg Häcker
Published online: September 2009
Dismantling the Apoptotic Cell
Paula Deming, Sally Kornbluth
Published online: December 2009
Caspases, Substrates and Sequential Activation
John G Walsh, Seamus J Martin
Published online: December 2009
BH3‐only Proteins
Lina Happo, Andreas Strasser, Clare L Scott
Published online: September 2009
Mitochondrial Outer Membrane Permeabilization
Melissa J Parsons, Douglas R Green
Published online: September 2009
Caspases in Inflammation and Immunity
Philippe M LeBlanc, Maya Saleh
Published online: September 2009