Biology of Ageing

Ageing is the single largest risk factor for disease in developed countries, and poses a great challenge both socially and economically. A selection of articles shows how research into ageing involves the elucidation of the basic biochemical, genetic, physiological, and neurological mechanisms underlying the process of ageing and analyzes how nutrition, environment and exercise can influence ageing.


History of Research into Ageing/Senescence
Andrea Grignolio, Claudio Franceschi
Published online: June 2012
Ageing
Mitchell Turker
Published online: March 2009
Ageing – Future Directions for Research in the Biology of Ageing
Thomas BL Kirkwood
Published online: May 2003
Ageing Genes: Gerontogenes
Suresh IS Rattan
Published online: May 2005
Ageing and the Brain
Naftali Raz
Published online: September 2005
Ageing and the Immune System
Richard Aspinall
Published online: September 2005
Ageing as a Global Challenge in the New Millennium
John Grimley Evans
Published online: September 2005
Telomeres and Telomerase in Ageing and Cancer
Michel M Ouellette, Kyung Hyun Choi
Published online: September 2007
Telomeres in Cell Function: Cancer and Ageing
Mary‐Lou Pardue, Gregory DeBaryshe
Published online: September 2009
Osteoarthritis
Constance R Chu, Thomas S Thornhill
Published online: April 2001
Osteoporosis and Osteopetrosis
Yousef Abu‐Amer, Isra Darwech, Jesse Otero
Published online: September 2007
Osteoporosis: Genetics
Wen‐Feng Li, Shu‐Xun Hou, Claude Férec, Jian‐Min Chen
Published online: April 2011
Life History Theory
Lev Y Yampolsky
Published online: July 2003
Cardiovascular Disease and Congenital Heart Defects
Qing Wang, Qiuyun Chen
Published online: April 2006
Heart Failure: Introduction
Andrew JS Coats
Published online: September 2005
Heart Failure
Philip A Poole‐Wilson, Rakesh Sharma, Aidan Bolger
Published online: April 2001
Ischaemic Heart Disease
David Lewis, Qing Wang, Eric Topol
Published online: April 2001
Metabolic Effects of Caloric Restriction
Joseph A Baur
Published online: March 2009
Alzheimer Disease: Genetic and Environmental Influences
Chandra A Reynolds
Published online: January 2013
Alzheimer Disease, Genetics of
Patrick G Kehoe
Published online: September 2008
Antioxidants
Laura Dugo, Yesim Negis, Angelo Azzi
Published online: February 2011
Cell Senescence In Vitro
Suresh IS Rattan
Published online: February 2012
Stress‐induced Premature Senescence (SIPS)
Olivier Toussaint, Michel Salmon, Thierry Pascal, Joao Pedro Magalhaes, Florence Chainiaux
Published online: May 2005
Aging: Genetics
Bastiaan Johannes Zwaan
Published online: January 2006
Mitochondria as a Key Determinant of Aging
Ludivine Walter, Siu Sylvia Lee
Published online: March 2009