Pathogenic Viruses: Clinical Detection


The clinical and laboratory diagnosis of the viral aetiology of an individual's illness involves understanding their clinical symptoms and signs, how the host's immune system responds to a viral infection, as well as which diagnostic tests are the most sensitive and specific to detect that virus or the host's immune response. Once the choice of test is made, the correct specimen must be collected and the results of these tests interpreted in the context of the clinical picture.

Keywords: signs; symptoms; syndrome; antibody; antigen; nucleic acid

Further Reading

Lab Tests Online

Lennette EH, Lennette DA and Lennette ET (eds) (1995) Diagnostic Procedures for Viral, Rickettsial and Chlamidial Infections. Washington, DC: American Public Health Association.

Mackay IM, Arden KE and Nitsche A (2002) Real‐time PCR in virology. Nucleic Acids Research 30: 1292–1305.

Topley and Wilson's Microbiology and Microbial Infections 10th edition – Virology edited by Brian WJ Mahy and Volker ter Meulen. London Hodder Arnold 2006.

Yang S and Rothman R (2004) PCR‐based diagnostics for infectious diseases: uses, limitations, and future applications in acute‐care settings. The Lancet Infectious Diseases 4: 337–348.

Contact Editor close
Submit a note to the editor about this article by filling in the form below.

* Required Field

How to Cite close
Zuckerman, Mark(Mar 2009) Pathogenic Viruses: Clinical Detection. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0001093.pub2]