Evolution of Genome Organization


Several features of chromosomes, such as chromosome number, polyploidy and the accumulation of repetitive DNA sequences near centromeres, reflect the evolutionary forces acting on eukaryotic genomes.

Keywords: chromosome number; chromosome rearrangements; polyploidy; repetitive DNA; recombination; natural selection


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Further Reading

Cavalier‐Smith T (ed.) (1985) The Evolution of Genome Size. Chichester, UK: Wiley.

Charlesworth B, Sniegowski P and Stephan W (1994) The evolutionary dynamics of repetitive DNA in eukaryotes. Nature 371: 215–220.

John B and Miklos GLG (1988) The Eukaryote Genome in Development and Evolution. London: Allen and Unwin.

Kapranov P, Willingham AT and Gingeras TR (2007) Genome‐wide transcription and the implications for genomic organization. Nature Reviews Genetics 8: 413–423.

Mewborn SK, Lese Martin C and Ledbetter DH (2005) The dynamic nature and evolutionary history of subtelomeric and pericentromeric regions. Cytogenetic and Genome Research 108: 22–25.

Ohno S (1970) Evolution by Gene Duplication. Berlin: Springer‐Verlag.

Vinogradov AE (2004) Evolution of genome size: multilevel selection, mutation bias or dynamical chaos? Current Opinion in Genetic Devision 14: 620–626.

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Stephan, Wolfgang(Dec 2007) Evolution of Genome Organization. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0001699.pub2]