Evolution: Selectionist View


The selectionist view of molecular evolution maintains that a large fraction of molecular variation seen in natural populations is due to beneficial mutations.

Keywords: molecular; variation; selection

Further Reading

Bernardi G (2007) The neoselectionist theory of genome evolution. Proceedings of the National Academy of Science of the USA 104(20): 8385–8390.

Bustamante CD, Fledel‐Alon A, Williamson S et al. (2005) Natural selection on protein‐coding genes in the human genome. Nature 437: 1153–1157.

Ewens WJ (1977) Population genetics theory in relation to the neutralist‐selectionist controversy. Advances in Human Genetics 8: 67–134.

Gillespie J (1991) The Causes of Molecular Evolution. New York: Oxford University Press.

Harris EE and Meyer D (2006) The molecular signature of selection underlying human adaptations. American Journal of Physical Anthropology 43(suppl.): 89–130.

Kimura M (1983) The Neutral Theory of Molecular Evolution. Cambridge, UK: Cambridge University Press.

Kreitman M and Akashi H (1995) Molecular evidence for natural selection. Annual Review of Ecology and Systematics 26: 403–422.

McVean G and Spencer CC (2006) Scanning the human genome for signals of selection. Current Opinion in Genetics & Development 16: 624–629.

Ponting CP and Lunter G (2006) Signatures of adaptive evolution within human non‐coding sequence. Human Molecular Genetics 15: R170–R175.

Ronald J and Akey JM (2005) Genome‐wide scans for loci under selection in humans. Human Genomics 2: 113–125.

Sunyaev S, Kondrashov FA, Bork P and Ramensky V (2003) Impact of selection, mutation rate and genetic drift on human genetic variation. Human Molecular Genetics 12: 3325–3330.

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How to Cite close
Wagner, Andreas(Dec 2007) Evolution: Selectionist View. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0005105.pub2]